Centre Publications 2017 - 2019

Agnieszka Tudek, A., M. Schmid, M. Makaras, J.D. Barrass, J.D., Beggs, and T. Heick Jensen (2018). “A nuclear export block triggers the decay of newly synthesized polyadenylated RNA”. Cell Reports, 24, 2457-2467, doi: 10.1016/j.celrep.2018.07.103

Agmon, N., Z. Tang, K. Yang, B. Sutter, S. Ikushima, Y. Cai, K. Caravelli, J.A. Martin, X. Sun, W.J. Choi, A. Zhang, G. Stracquadanio, H. Hao, B.P. Tu, D. Fenyo, J.S. Bader and J.D. Boeke (2017). "Low escape-rate genome safeguards with minimal molecular perturbation of Saccharomyces cerevisiae." Proc Natl Acad Sci U S A 114(8): E1470-E1479.

Allshire, R.C. and H.D. Madhani (2018). "Ten principles of heterochromatin formation and function”. Nat Rev Mol Cell Biol 19(4): 229-244.

Anedchenko, E.A., A. Samel-Pommerencke, T.M. Tran Nguyen, S. Shahnejat-Bushehri, J. Popsel, D. Lauster, A. Herrmann, J. Rappsilber, A. Cuomo, T. Bonaldi and A.E. Ehrenhofer-Murray (2019). "The kinetochore module Okp1(CENP-Q)/Ame1(CENP-U) is a reader for N-terminal modifications on the centromeric histone Cse4(CENP-A)”. EMBO J 38(1).

Anselm, E., A.W. Thomae, A.A. Jeyaprakash and P. Heun (2018). “Oligomerisation of Drosophila Nucleophosmin-like protein is required for its centromere localisation”. Nucleic Acid Res 46: 11274-11286.

Antequera, F. and A. Bird (2018). "CpG Islands: A Historical Perspective." Methods Mol Biol 1766: 3-13.

Ard, R., R.C. Allshire and S. Marquardt (2017). "Emerging properties and functional consequences of noncoding transcription." Genetics 207(2): 357-367.

Aslanzadeh, V., Y. Huang, G. Sanguinetti and J.D. Beggs (2018). "Transcription rate strongly affects splicing fidelity and cotranscriptionality in budding yeast." Genome Res 28(2): 203-213.

Ballarino, M., A. Cipriano, R. Tita, T. Santini, F. Desideri, M. Morlando, A. Colantoni, C. Carrieri, C. Nicoletti, A. Musarò, D. O’Carroll and I. Bozzoni (2018). “Deficiency in the nuclear long noncoding RNA Charme causes myogenic defects and heart remodeling in mice”. EMBO 37(18). pii: e99697. doi: 10.15252/embj.201899697. Epub 2018 Sep 3. PubMed PMID: 30177572.

Bao, X.X., C. Spanos, T. Kojidani, E.M. Lynch, J. Rappsilber, Y. Hiraoka, T. Haraguchi and K.E. Sawin (2018). "Exportin Crm1 is repurposed as a docking protein to generate microtubule organizing centers at the nuclear pore." Elife 7.

Barrey, E.J. and Heun, P. (2017). “Artificial chromosomes and strategies to initiate epigenetic centromere establishment”. Prog Mol Subcell Biol 56: 193-212.

Beaven, R., R.N. Bastos, C. Spanos, P. Rome, C.F. Cullen, J. Rappsilber, R. Giet, G. Goshima and H. Ohkura (2017). "14-3-3 regulation of Ncd reveals a new mechanism for targeting proteins to the spindle in oocytes." J Cell Biol 216(10): 3029-3039.

Beggs, J.D. (2017). "Pre-mRNA Splicing." In Reference Module in Life Sciences, Elsevier, 2017, ISBN: 978-0-12-809633-8, http://dx.doi.org/10.1016/B978-0-12-809633-8.06947-8.

Belsom, A., G. Mudd, S. Giese, M. Auer and J. Rappsilber (2017). "Complementary Benzophenone Cross-Linking/Mass Spectrometry Photochemistry." Anal Chem 89(10): 5319-5324.

Bharathavikru, R., T. Dudnakova, S. Aitken, J. Slight, M. Artibani, P. Hohenstein, D. Tollervey and N. Hastie (2017). "Transcription factor Wilms' tumor 1 regulates developmental RNAs through 3' UTR interaction." Genes Dev 31(4): 347-352.

Bikkul, M.U., R.G.A. Faragher, G. Worthington, P. Meinke, A.R.W. Kerr, A. Sammy, K. Riyahi, D. Horton, E.C. Schirmer, M. Hubank, I.R. Kill, R.M. Anderson, P. Slijepcevic, E. Makarov and J.M. Bridger (2018). "Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson-Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform." Genes Chromosomes Cancer doi: 10.1002/gcc.22711. PMID:30474255

Bird, A. (2017). "Genetic determinants of the epigenome in development and cancer." Swiss Med Wkly 147: w14523.

Bitetti, A., A.C. Mallory, E. Golini, C. Carrieri,  H. Carreño Gutiérrez, E. Perlas, Y.A. Pérez-Rico, G.P. Tocchini-Valentini, A.J. Enright, W.H.J. Norton, S. Mandillo, D. O'Carroll, and A. Shkumatava (2018). “MicroRNA degradation by a conserved target RNA regulates animal behaviour”. Nat Struct Mol Biol. 25(3):244-251.

Blyth, J., V. Makrantoni, R.E. Barton, C. Spanos, J. Rappsilber and A.L. Marston (2018). "Genes important for Schizosaccharomyces pombe meiosis identified through a functional genomics screen." Genetics 208(2): 589-603.

Bobkov, G.O.M., N. Gilbert and P. Heun (2018). "Centromere transcription allows CENP-A to transit from chromatin association to stable incorporation." J Cell Biol 217: 1957-1972.

Booth, D.G. and W.C. Earnshaw (2017). "Ki-67 and the chromosome periphery compartment in mitosis." Trends Cell Biol 27(12): 906-916.

Borek, W. and A.L. Marston (2018). “Diverse model systems reveal common principles of meiosis”. Genome Biology 19: 134.

Bresson, S. and D. Tollervey (2018). "Surveillance-ready transcription: nuclear RNA decay as a default fate." Open Biol 8(3).

Bresson, S., A. Tuck, D. Staneva and D. Tollervey (2017). "Nuclear RNA decay pathways aid rapid remodeling of gene expression in yeast." Mol Cell 65(5): 787-800 e785.

Bresson, S. and D. Tollervey (2018). “Tailing off: PABP and CNOT generate cycles of mRNA deadenylation”. Mol. Cell, 70: 987–988. PMID: 29932908.

Burmann, F., B.G. Lee, T. Than, L. Sinn, F.J. O'Reilly, S. Yatskevich, J. Rappsilber, B. Hu, K. Nasmyth and J. Lowe (2019). "A folded conformation of MukBEF and cohesin." Nat Struct Mol Biol 26(3): 227-236.

Cai, Y. and J. Dai (2017). "Methods to synthesize large DNA fragments for a synthetic yeast genome." Cold Spring Harb Protoc 2017(3): pdb prot080978.

Capitanchik, C., C. Dixon, S.K. Swanson, L. Florens, A.R.W. Kerr and E.C. Schirmer (2018). “Analysis of RNA-Seq datasets reveals enrichment of tissue-specific splice variants for nuclear envelope proteins”.  Nucleus 9(1), 410-430. PMID:29912636.

Carpy, A., A. Koch, C.C. Bicho, W.E. Borek, S. Hauf, K.E. Sawin and B. Macek (2017). "Stable isotope labeling by amino acids in cell culture (SILAC)-based quantitative proteomics and phosphoproteomics in fission yeast." Cold Spring Harb Protoc (6): pdb prot091686.

Carrieri, C., S. Comazzetto, A. Grover, M. Morgan, A. Buness, C. Nerlov and D. O'Carroll (2017). "A transit-amplifying population underpins the efficient regenerative capacity of the testis." J Exp Med 214(6): 1631-1641.

Cheerambathur, D.K., B. Prevo, T-L. Chow, N. Hattersley, S. Wang, Z. Zhao, T. Kim, A. Gerson-Gurwitz, K. Oegema, R. Green, R., et al. (2019). The kinetochore-microtubule coupling machinery Is repurposed in sensory nervous system morphogenesis. Dev. Cell.

Chen, J.W.C., A.A. Chen, K.B. Rogala, J. Metz, C.M. Deane, J. Rappsilber, and J.G. Wakefield (2017). “Cross-linking mass spectrometry identifies new interfaces of Augmin required to localise the γ-tubulin ring complex to the mitotic spindle”. Biol. Open 6: 654–663.

Chen, Z.A. and J. Rappsilber (2018). "Protein dynamics in solution by quantitative crosslinking/mass spectrometry." Trends Biochem Sci 43(11): 908-920.

Chen, Z.A. and J. Rappsilber (2019). "Quantitative cross-linking/mass spectrometry to elucidate structural changes in proteins and their complexes." Nat Protoc 14(1): 171-201.

Choudhury, N.R., G. Heikel, M. Trubitsyna, P. Kubik, J.S. Nowak, S. Webb, S. Granneman, C. Spanos, J. Rappsilber, A. Castello and G. Michlewski (2017). "RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination." BMC Biol 15(1): 105.

Combe, C.W., M.D. Sivade, H. Hermjakob, J. Heimbach, B.H.M. Meldal, G. Micklem, S. Orchard and J. Rappsilber (2017). "ComplexViewer: visualization of curated macromolecular complexes." Bioinformatics 33(22): 3673-3675.

Combes G., H. Barysz, C. Garand, L. Gama Braga, I. Alharbi, P. Thebault, L. Murakami, D.P. Bryne, S. Stankovic, P.A. Eyers, V.M. Bolanos-Garcia, W.C. Earnshaw, J. Maciejowski, P.V. Jallepalli and S. Elowe. (2018). “Mps1 phosphorylates its N-terminal extension to relieve autoinhibition and activate the spindle assembly checkpoint”. Curr Biol. 28: 872-883.

Crozier, T.W.M., M. Tinti, R.J. Wheeler, T. Ly, M.A.J. Ferguson and A.I. Lamond (2018). "Proteomic analysis of the cell cycle of procylic form Trypanosoma brucei." Mol. Cell. Proteomics 17: 1184-1195.

Cruz, M., M.A, Abad, W. van Ijcken, N. Galjart, A.A. Jeyaprakash, H. Maiato, and C. Ferrás (2018). Mitotic progression, arrest, exit or death is determined by centromere integrity and independent of de novo transcription. eLife 7:e36898 DOI: 10.7554/elLife.36898

Davis, M.P., C. Carrieri, H.K. Saini, S. van Dongen, T. Leonardi, G. Bussotti, J.M. Monahan, T. Auchynnikava, A. Bitetti, J. Rappsilber, R.C. Allshire, A. Shkumatava, D. O'Carroll and A.J. Enright (2017). "Transposon-driven transcription is a conserved feature of vertebrate spermatogenesis and transcript evolution." EMBO Rep 18(7): 1231-1247.

Dau, T., K. Gupta, I. Berger and J. Rappsilber (2019). "Sequential digestion with trypsin and elastase in cross-linking mass spectrometry." Anal Chem.

de Castro, I.J., J. Budzak, M.L. Di Giacinto, L. Ligammari, E. Gokhan, C. Spanos, D. Moralli, C. Richardson, J.I. de Las Heras, S. Salatino, E.C. Schirmer, K.S. Ullman, W.A. Bickmore, C. Green, J. Rappsilber, S. Lamble, M.W. Goldberg, V. Vinciotti and P. Vagnarelli (2017). "Repo-Man/PP1 regulates heterochromatin formation in interphase." Nat Commun 8: 14048.

de Las Heras, J.I., N. Zuleger, D.G. Batrakou, R. Czapiewski, A.R. Kerr and E.C. Schirmer (2017). "Tissue-specific NETs alter genome organization and regulation even in a heterologous system." Nucleus 8(1): 81-97.

de la Roche, M., D. Hamilton, R. Mortensen, A.A. Jeyaprakash, S. Gosh, and P.K. Anand (2018). Trafficking of cholesterol to the ER is required for NLRP3 inflammasome activation. J Cell Biol DOI: 10.1083/jcb.201709057.

Delan-Forino, C., C. Schneider and D. Tollervey (2017) Transcriptome-wide analysis of alternative routes for RNA substrates into the exosome complex. PLoS Gen. 13, e1006699. PMCID:PMC5389853

Delan-Forino, C., C. Schneider and D. Tollervey (2017). "RNA substrate length as an indicator of exosome interactions in vivo." Wellcome Open Res 2: 34.

Deretic J., A. Kerr and J.P.I. Welburn (2019). “A rapid computational approach identifies SPICE1 as an Aurora kinase substrate”. MBOC (30):312-323. PMID: 3048516.

Dixon, C.R. and E.C. Schirmer (2018). “Navigating the nuclear envelope: one or multiple transport mechanisms for integral membrane proteins?” In Nuclear-cytoplasmic transport from Springer Nucleic Acids and Molecular Biology series Vol 33, ed. Maximillian D'Angelo. Springer, chpt. 7 (pp 151-178). ISBN 978-3-319-77308-7.

Dixon, C.R., M. Platani, A.A. Makarov and E.C. Schirmer (2017). "Microinjection of antibodies targeting the lamin A/C histone-binding site blocks mitotic entry and reveals separate chromatin interactions with HP1, CenpB and PML." Cells 6(2).

Downie Ruiz Velasco, A., S.M.J. Welten, E.A.C. Goossens, P.H.A. Quax, J. Rappsilber, G. Michlewski and A.Y. Nossent (2019). "Posttranscriptional regulation of 14q32 MicroRNAs by the CIRBP and HADHB during vascular regeneration after ischemia." Mol Ther Nucleic Acids 14: 329-338.

Dudnakova, T., H. Dunn-Davies, R. Peters and D. Tollervey (2018). “Mapping targets for small nucleolar RNAs in yeast”. Wellcome Open Res. 3: 120. doi:10.12688/wellcomeopenres.14735.1

El Hage, A. and D. Tollervey (2018). "Immunoprecipitation of RNA:DNA hybrids from budding yeast." Methods Mol Biol 1703: 109-129.

Fischer, L. and J. Rappsilber (2018). "False discovery rate estimation and heterobifunctional cross-linkers." PLoS One 13(5): e0196672.

Fischer, L. and J. Rappsilber (2017). "Quirks of error estimation in cross-linking/mass spectrometry." Anal Chem 89(7): 3829-3833.

Fox, C., J. Zou, J. Rappsilber and A.L. Marston (2017). "Cdc14 phosphatase directs centrosome re-duplication at the meiosis I to meiosis II transition in budding yeast." Wellcome Open Res 2: 2.

Galander, S., R.E. Barton, D.A. Kelly and A.L. Marston (2019). “Spo13 prevents premature cohesin cleavage during meiosis” [version 1; referees: 1 approved with reservations]. Wellcome Open Res 4: 29.

Gatticchi, L., J.I. de las Heras, R. Roberti and E.C. Schirmer (2018). “Optimization of DamID for use in primary cultures of mouse hepatocytes”. Methods pii: S1046-2023(18)30119-1. PMID:30445179.

Gautam, A. and J.D. Beggs (2019). “Mutagenesis of Snu114 domain IV identifies a developmental role in meiotic splicing”. RNA Biology 16: 185–195. doi: 10.1080/15476286.2018.1561145

Georgiou, C., I. McNae, M. Wear, H. Ioannidis, J. Michel and M. Walkinshaw (2017). "Pushing the limits of detection of weak binding using fragment-based drug discovery: identification of new cyclophilin binders." J Mol Biol 429(16): 2556-2570.

Gerboth, S., E. Frittoli, A. Palamidessi, F.C. Baltanas, M. Salek, J. Rappsilber, C. Giuliani, F. Troglio, Y. Rolland, G. Pruneri, S. Kreutmair, I. Pallavicini, M. Zobel, M. Cinquanta, S. Minucci, C. Gomez, E. Santos, A.L. Illert and G. Scita (2018). "Phosphorylation of SOS1 on tyrosine 1196 promotes its RAC GEF activity and contributes to BCR-ABL leukemogenesis." Leukemia 32(3): 820-827.

Gibcus, J.H., K. Samejima, A. Goloborodko, I. Samejima, N. Naumova, J. Nuebler, M.T. Kanemaki, L. Xie, J.R. Paulson, W.C. Earnshaw, L.A. Mirny and J. Dekker (2018). "A pathway for mitotic chromosome formation." Science 9:359(6376).

Giese, S.H., A. Belsom and J. Rappsilber (2017). "Correction to optimized fragmentation regime for diazirine photo-cross-linked peptides." Anal Chem 89(6): 3802-3803.

Gigant, E., M. Stefanutti, K. Laband, A. Gluszek-Kustusz, F. Edwards, B. Lacroix, G. Maton, J.C. Canman, J.P.I. Welburn and J. Dumont (2017). "Inhibition of ectopic microtubule assembly by the kinesin-13 KLP-7 prevents chromosome segregation and cytokinesis defects in oocytes." Development 144(9): 1674-1686.

Giotti, B., S. Chen, M.W. Barnett, T. Regan, T. Ly, S. Wiemann, D.A. Hume and T. Freeman (2018). "Assembly of a parts list of the human mitotic cell cycle machinery." J Mol Cell Biol mjy063, https://doi.org/10.1093/jmcb/mjy063.

Guitart, A.V., T.I. Panagopoulou, A. Villacreces, M. Vukovic, C. Sepulveda, L. Allen, R.N. Carter, L. N. van de Lagemaat, M. Morgan, P. Giles, Z. Sas, M.V. Gonzalez, H. Lawson, J. Paris, J. Edwards-Hicks, K. Schaak, C. Subramani, D. Gezer, A. Armesilla-Diaz, J. Wills, A. Easterbrook, D. Coman, C.W. So, D. O'Carroll, D. Vernimmen, N.P. Rodrigues, P.J. Pollard, N.M. Morton, A. Finch and K.R. Kranc (2017). "Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions." J Exp Med 214(3): 719-735.

Gupta, K., A.A. Watson, T. Baptista, E. Scheer, A.L. Chambers, C. Koehler, J. Zou, I. Obong-Ebong, E. Kandiah, A. Temblador, A. Round, E. Forest, P. Man, C. Bieniossek, E.D. Laue, E.A. Lemke, J. Rappsilber, C.V. Robinson, D. Devys, L. Tora and I. Berger (2017). "Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID." Elife 6.

Guy, J., B. Alexander-Howden, L. FitzPatrick, D. DeSousa, M. V. Koerner, J. Selfridge and A. Bird (2018). "A mutation-led search for novel functional domains in MeCP2." Hum Mol Genet 27(14): 2531-2545.

Hegarat, N., A. Crncec, M.F. Rodriguez, F. Iturra, Y. Gu, P.F. Lang, A.R. Barr, C. Bakal,  M.T. Kanemaki, A.I. Lamond, B. Novak, T. Ly and H. Hochegger (2018). “Cyclin A triggers mitosis either via Greatwall or Cyclin B”. bioRxiv https://dx.doi.org/10.1101/501684.

Heyn, P., C.V. Logan, A. Fluteau, R.C. Challis,, T. Auchynnikava, C.A. Martin, J.A. Marsh, F. Taglini, F. Kilanowski, D.A. Parry, V. Cormier-Daire, C.T. Fong, K. Gibson, V. Hwa, L. Ibáñez, S.P. Robertson, G. Sebastiani, J. Rappsilber, R.C. Allshire, M.A.M. Reijns, A. Dauber, D. Sproul, A.P. Jackson (2019). “Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions”. Nat Genet. 51:96-105.

Hinshaw, S.M., V. Makrantoni, S.C. Harrison and A.L. Marston (2017). "The kinetochore receptor for the cohesin loading complex." Cell 171(1): 72-84 e13.

Ivanova, I., C. Much, M. Di Giacomo, C. Azzi, M. Morgan, P.N. Moreira, J. Monahan, C. Carrieri, A.J. Enright and D. O'Carroll (2017). "The RNA m(6)A Reader YTHDF2 is essential for the post-transcriptional regulation of the maternal transcriptome and oocyte competence." Mol Cell 67(6): 1059-1067 e1054.

Jacob, Y. and P. Voigt (2018). "In Vitro Assays to Measure Histone Methyltransferase Activity Using Different Chromatin Substrates." Methods Mol Biol 1675: 345-360.

Jantsch, M.F., A. Quattrone, M. O'Connell, M. Helm, M. Frye, M. Macias-Gonzales M, M. Ohman, S. Ameres, L. Willems, F. Fuks, A. Oulas, S. Vanacova, H. Nielsen, C. Bousquet-Antonelli C, Motorin Y, Roignant JY, Balatsos N, Dinnyes A, Baranov P,Kelly V, Lamm A, G. Rechavi, M. Pelizzola et al and D. O Carroll, J. Ule and R. Fray (2018) “Positioning Europe for the EPITRANSCRIPTOMICS challenge”. RNA Biol. 9:1-3. doi:10.1080/15476286.2018.1460996. [Epub ahead of print] PubMed PMID: 29671387.

Kastritis, P.L., F.J. O'Reilly, T. Bock, Y. Li, M.Z. Rogon, K. Buczak, N. Romanov, M.J. Betts, K.H. Bui, W.J. Hagen, M.L. Hennrich, M.T. Mackmull, J. Rappsilber, R.B. Russell, P. Bork, M. Beck and A.C. Gavin (2017). "Capturing protein communities by structural proteomics in a thermophilic eukaryote". Mol Syst Biol 13(7): 936.

Kitevski-LeBlanc, J., A. Fradet-Turcotte, P. Kukic, M.D. Wilson, G. Portella, T. Yuwen, S. Panier, S. Duan, M.D. Canny, H. van Ingen, C.H. Arrowsmith, J.L. Rubinstein, M. Vendruscolo, D. Durocher and L.E. Kay (2017). "The RNF168 paralog RNF169 Defines a new class of ubiquitylated histone reader involved in the response to DNA

damage". Elife 6.

Koch, A., C.C. Bicho, W.E. Borek, A. Carpy, B. Macek, S. Hauf and K.E. Sawin (2017). "Construction, growth, and harvesting of fission yeast stable isotope labeling by amino acids in cell culture (SILAC) strains." Cold Spring Harb Protoc (6): pdb prot091678.

Koerner, M.V., L. FitzPatrick, J. Selfridge, J. Guy, D. De Sousa, R. Tillotson, A. Kerr, Z. Sun, M.A. Lazar, M.J. Lyst and A. Bird (2018). "Toxicity of overexpressed MeCP2 is independent of HDAC3 activity". Genes Dev 32(23-24): 1514-1524.

Kolbowski, L., M.L. Mendes and J. Rappsilber (2017). "Optimizing the parameters governing the fragmentation of cross-linked peptides in a Tribrid mass spectrometer". Anal Chem 89(10): 5311-5318.

Kouprina N., N. Petrov, O. Molina, M. Liskovykh, E. Pesenti, J.I. Ohzeki, H. Masumoto, W.C. Earnshaw and V. Larionov. (2018). “Human artificial chromosome with regulated centromere: a tool for genome and cancer studies”.  ACS Synth Biol. 7: 1974-1989.

Kozlowski, E., G.A. Wasserman, M. Morgan, D. O'Carroll, N.P. Ramirez, S. Gummuluru, J.Y. Rah, A.C. Gower, M. Ieong, L.J. Quinton, J.P. Mizgerd and M.R. Jones (2017). "The RNA uridyltransferase Zcchc6 is expressed in macrophages and impacts innate immune responses." PLoS One 12(6): e0179797.

Kruusvee, V., M.J. Lyst, C. Taylor, Z. Tarnauskaite, A.P. Bird and A.G. Cook (2017). "Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders." Proc Natl Acad Sci USA 114(16): E3243-E3250.

Kulasegaran-Shylini, R., L. Subramanian, A.R.W. Kerr, C. Spanos, J. Rappsilber and R.C. Allshire (2018). "Swr1-mediated H2A.Z incorporation designates centromere DNA for de novo CENP-A assembly." bioRxiv [Nov 2017.

Kyriacou, E. and Heun, P. (2018). “High-resolution mapping of centromeric protein association using APEX-chromatin fibers”. Epigenetics Chromatin 11: 68.

Ladds, M., I.M.M. van Leeuwen, C.J. Drummond, S. Chu, A.R. Healy, G. Popova, A. Pastor Fernandez, T. Mollick, S. Darekar, S.K. Sedimbi, M. Nekulova, M.C.C. Sachweh, J. Campbell, M. Higgins, C. Tuck, M. Popa, M.M. Safont, P. Gelebart, Z. Fandalyuk, A.M. Thompson, R. Svensson, A.L. Gustavsson, L. Johansson, K. Farnegardh, U. Yngve, A. Saleh, M. Haraldsson, A.C.A. D'Hollander, M. Franco, Y. Zhao, M. Hakansson, B. Walse, K. Larsson, E. M. Peat, V. Pelechano, J. Lunec, B. Vojtesek, M. Carmena, W.C. Earnshaw A.R. McCarthy, N.J. Westwood, M. Arsenian-Henriksson, D.P. Lane, R. Bhatia, E. McCormack and S. Lain (2018). "A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage." Nat Commun 9(1): 1107.

Lagger, S., J.C. Connelly, G. Schweikert, S. Webb, J. Selfridge, B.H. Ramsahoye, M. Yu, C. He, G. Sanguinetti, L.C. Sowers, M.D. Walkinshaw and A. Bird (2017). "MeCP2 recognizes cytosine methylated tri-nucleotide and di-nucleotide sequences to tune transcription in the mammalian brain." PLoS Genet 13(5): e1006793.

Lee, N.C.O., J.H. Kim, N.S. Petrov, H.S. Lee, H. Masumoto, W.C. Earnshaw, V. Larionov and N. Kouprina (2018). "Method to assemble genomic DNA fragments or genes on human artificial chromosome with regulated kinetochore using a multi-integrase system." ACS Synth Biol 7(1): 63-74.

Lee, H.S., M. Carmena, M. Liskovykh, E. Peat, J.H. Kim, M. Oshimura, H. Masumoto, M.P. Teulade-Fichou, Y. Pommier, W.C. Earnshaw, V. Larionov and N. Kouprina (2018). Systematic analysis of compounds specifically targeting telomeres and telomerase for clinical implications in cancer therapy”.  Cancer Res 78: 6282-6296.

Lenz, S., S.H. Giese, L. Fischer and J. Rappsilber (2018). "In-search assignment of monoisotopic peaks improves the identification of cross-linked peptides." J Proteome Res 17(11): 3923-3931.

Le Pen J., H. Jiang, T. Di Domenico, E. Kneuss, J. Kosałka, C. Leung, M. Morgan, C. Much, K.L.M. Rudolph, A.J. Enright, D. O'Carroll, D. Wang, and E.A. Miska (2018). “Terminal uridylyltransferases target RNA viruses as part of the innate immune system”. Nat Struct Mol Biol. 25(9): 778-786. doi: 10.1038/s41594-018-0106-9. Epub 2018 Aug 13. PubMed PMID: 30104661.

Le Thanh, P., P. Meinke, N. Korfali, V. Srsen, M.I. Robson, M. Wehnert, B. Schoser, C.A. Sewry and E.C. Schirmer (2017). "Immunohistochemistry on a panel of Emery-Dreifuss muscular dystrophy samples reveals nuclear envelope proteins as inconsistent markers for pathology." Neuromuscul Disord 27(4): 338-351.

Liakath-Ali, K., E.W. Mills, I. Sequeira, B.M. Lichtenberger, A.O. Pisco, K.H. Sipila, A. Mishra, H. Yoshikawa, C.C. Wu, T. Ly, A.I. Lamond, I.M. Adham, R. Green and F.M. Watt (2018). "An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis." Nature 556: 376-380.

Ly, T., A. Endo, A. Brenes, M. Gierlinski, V. Afzal, A. Pawellek, A.I. Lamond (2018). “Proteome-wide analysis of protein abundance and turnover remodeling during oncogenic transformation of human breast epithelial cells”. Wellcome Open Res. 3: 51.

Ly, T., A. Whigham, R. Clarke, A.J. Brenes-Murillo, B. Estes, D. Madhessian, E. Lundberg, P. Wadsworth and A.I. Lamond (2017). "Proteomic analysis of cell cycle progression in asynchronous cultures, including mitotic subphases, using PRIMMUS." Elife 6 e27574.

Lyst, M.J., R. Ekiert, J. Guy, J. Selfridge, M.V. Koerner, C. Merusi, D. De Sousa and A. Bird (2018). "Affinity for DNA contributes to NLS independent nuclear localization of MeCP2." Cell Rep 24(9): 2213-2220.

Macek, B., A. Carpy, A. Koch, C.C. Bicho, W.E. Borek, S. Hauf and K.E. Sawin (2017). "Stable isotope labeling by amino acids in cell culture (SILAC) technology in fission yeast." Cold Spring Harb Protoc 2017(6): pdb top079814.

Makrantoni, V. and A.L. Marston (2018). “Cohesin and chromosome segregation”. Current Biology 28(12):R688-R693.

Makrantoni, V., A. Ciesiolka, C. Lawless, J. Fernius, A.L. Marston, D. Lydall and M.J.R. Stark (2017). “A functional link between Bir1 and the Saccharomyces cerevisiae Ctf19 kinetochore complex revealed through quantitative fitness analysis”. G3. 7, 3203-3215.

Marston, A.L. (2017). "Dalmatian: spotting the difference in cohesin protectors." EMBO J 36(11): 1468-1470.

Marston, A.L. and K. Wassmann (2017). "Multiple duties for spindle assembly checkpoint kinases in meiosis." Front Cell Dev Biol 5: 109.

May, S., H. Owen, T.J. Phesse, K.R. Greenow, G.R. Jones, A. Blackwood, P.C. Cook, C. Towers, A.M. Gallimore, G.T. Williams, M. Sturzl, N. Britzen-Laurent, O.J. Sansom, A.S. MacDonald, A.P. Bird, A.R. Clarke and L. Parry (2018). "Mbd2 enables tumourigenesis within the intestine while preventing tumour-promoting inflammation." J Pathol 245(3): 270-282.

McHugh, T., J. Zou, V.A. Volkov, A. Bertin, S.K. Talapatra, J. Rappsilber, M. Dogterom and J.P.I. Welburn (2019). "The depolymerase activity of MCAK shows a graded response to Aurora B kinase phosphorylation through allosteric regulation." J Cell Sci 132(4).

McHugh T., A. Gluszek-Kustusz, J.P.I. Welburn (2018). “Kinesin-8 motor Kif18b tethering to microtubule ends is a requirement for spindle positioning”. J Cell Biol 217:7. 2403-2416. PMID:  29661912

McHugh, T. and J.P. Welburn (2017). "Dynein at kinetochores: Making the connection." J Cell Biol 216(4): 855-857.

McAteer, S.P., B.M. Sy, J.L. Wong, D. Tollervey, D.L. Gally and J.J. Tree (2018). “Ribosome maturation by the endoribonuclease YbeY stabilizes a type 3 secretion system transcript required for virulence of enterohemorrhagic Escherichia coli”. J. Biol. Chem. 293. 9006-9016. PMID: PMC5995498

Mendoza-Ochoa, G.I., J.D. Barrass, B.R. Terlouw, I.E. Maudlin, S. de Lucas, E. Sani, V. Aslanzadeh, J.A.E. Reid, and J.D. Beggs, (2019). “A fast and tuneable auxin-inducible degron for depletion of target proteins in budding yeast”. Yeast 36: 75-81, doi: 10.1002/yea.3362.

Mercy, G., J. Mozziconacci, V.F. Scolari, K. Yang, G. Zhao, A. Thierry, Y. Luo, L.A. Mitchell, M. Shen, Y. Shen, R. Walker, W. Zhang, Y. Wu, Z. X. Xie, Z. Luo, Y. Cai, J. Dai, H. Yang, Y. J. Yuan, J.D. Boeke, J.S. Bader, H. Muller and R. Koszul (2017). "3D organization of synthetic and scrambled chromosomes." Science 355(6329).

Milligan, L., C. Sayou, A. Tuck, T. Auchynnikava, J.E. Reid, R. Alexander, F.L. Alves, R. Allshire, C. Spanos, J. Rappsilber, J.D. Beggs, G. Kudla and D. Tollervey (2017). "RNA polymerase II stalling at pre-mRNA splice sites is enforced by ubiquitination of the catalytic subunit." Elife 6, pii: e27082. doi: 10.7554/eLife.27082.

Mishra, A., B. Oules, A.O. Pisco, T. Ly, K. Liakath-Ali, G. Walko, P. Viswanathan, M. Tihy, J. Nijjher, S.J. Dunn, A.I. Lamond and F.M. Watt (2017). "A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis." Elife 6.

Mitchell, L.A., A. Wang, G. Stracquadanio, Z. Kuang, X. Wang, K. Yang, S. Richardson, J.A. Martin, Y. Zhao, R. Walker, Y. Luo, H. Dai, K. Dong, Z. Tang, Y. Yang, Y. Cai, A. Heguy, B. Ueberheide, D. Fenyo, J. Dai, J.S. Bader and J.D. Boeke (2017). "Synthesis, debugging, and effects of synthetic chromosome consolidation: synVI and beyond." Science 355(6329).

Molina, O., N. Kouprina, H. Masumoto, V. Larionov and W.C. Earnshaw (2017). "Using human artificial chromosomes to study centromere assembly and function." Chromosoma 126(5): 559-575.

Montano-Gutierrez, L.F., S. Ohta, G. Kustatscher, W.C. Earnshaw and J. Rappsilber (2017). "Nano Random forests to mine protein complexes and their relationships in quantitative proteomics data." Mol Biol Cell 28: 673-680.

Morgan, M., Y. Kabayama, C. Much, I. Ivanova, M. Di Giacomo, T. Auchynnikava,  J.M. Monahan, D.M. Vitsios, L. Vasiliauskaitė, S. Comazzetto J. Rappsilber, R.C. Allshire, B.T. Porse, A.J. Enright and D. O'Carroll (2019). “A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis”. Cell Res 29: 221-232.

Morgan, M., C. Much, M. DiGiacomo, C. Azzi, I. Ivanova, D. M. Vitsios, J. Pistolic, P. Collier, P.N. Moreira, V. Benes, A.J. Enright and D. O'Carroll (2017). "mRNA 3' uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome." Nature 548(7667): 347-351.

Muller, F., L. Fischer, Z.A. Chen, T. Auchynnikava and J. Rappsilber (2018). "On the reproducibility of label-free quantitative cross-linking/mass spectrometry." J Am Soc Mass Spectrom 29(2): 405-412.

Müller, F., L. Kolbowski, O.M. Bernhardt, Reiter, L. and Rappsilber, J. (2019). Data-independent acquisition improves quantitative cross-linking mass spectrometry. Mol. Cell. Proteomics.

Nowak, J.S., F. Hobor, A. Downie Ruiz Velasco, N.R. Choudhury, G. Heikel, A. Kerr, A. Ramos and G. Michlewski (2017). "Lin28a uses distinct mechanisms of binding to RNA and affects miRNA levels positively and negatively." RNA 23(3): 317-332.

Ogorzalek, T.L., G.L. Hura, A. Belsom, K.H. Burnett, A. Kryshtafovych, J.A. Tainer, J. Rappsilber, S.E. Tsutakawa and K. Fidelis (2018). "Small angle X-ray scattering and cross-linking for data assisted protein structure prediction in CASP 12 with prospects for improved accuracy." Proteins 86 Suppl 1: 202-214.

Ohta, S., T. Taniguchi, N. Sato, M. Hamada, H. Taniguchi and J. Rappsilber (2019). "Quantitative proteomics of the mitotic chromosome scaffold reveals the association of BAZ1B with chromosomal zxes." Mol Cell Proteomics 18(2): 169-181.

Ohzeki, J., N. Shono, K. Otake, N.M. Martins, K. Kugou, H. Kimura, T. Nagase, V. Larionov, W.C. Earnshaw and H. Masumoto (2016). "KAT7/HBO1/MYST2 regulates CENP-A chromatin assembly by antagonizing Suv39h1-mediated centromere inactivation." Dev Cell 37(5): 413-427.

Ongey, E.L., R.T. Giessmann, M. Fons, J. Rappsilber, L. Adrian and P. Neubauer (2018). "Heterologous biosynthesis, modifications and structural characterization of ruminococcin-A, a lanthipeptide from the gut bacterium Ruminococcus gnavus E1, in Escherichia coli." Front Microbiol 9: 1688.

O'Reilly, F.J. and J. Rappsilber (2018). "Cross-linking mass spectrometry: methods and applications in structural, molecular and systems biology." Nat Struct Mol Biol 25(11): 1000-1008.

Ozata, D.M., I. Gainetdinov, A. Zoch, D. O'Carroll, P.D. Zamore (2018). “PIWI-interacting RNAs: small RNAs with big functions”. Nat Rev Genet. 16. doi:10.1038/s41576-018-0073-3. [Epub ahead of print] Review. PubMed PMID: 30446728.

Peil, L., S. Waghmare, L. Fischer, M. Spitzer, D. Tollervey and J. Rappsilber (2018) “Identification of RNA-associated peptides, iRAP, defines precise sites of protein-RNA interaction”. bioRxiv, http://biorxiv.org/cgi/content/short/456111v1

Pesenti E., N. Kouprina, M. Liskovykh, J. Aurich-Costa, V. Larionov, H. Masumoto, W.C. Earnshaw and O. Molina. (2018). “Generation of a synthetic human chromosome with two centromeric domains for advanced epigenetic engineering studies”. ACS Synthetic Biology, 20: 1116-1130.

Platani M., I. Samejima, K. Samejima, M.T. Kanemaki and W.C. Earnshaw. (2018). “Seh1 targets GATOR2 and Nup153 to mitotic chromosomes”. J Cell Science 131: jcs213140.

Plowman, R., N. Singh, E. Duro, A. Payan, K.D. Corbett, and A.L. Marston (2019). “The molecular basis of monopolin recruitment to the kinetochore”. bioRxiv. https://doi.org/10.1101/456798.

Richardson, S.M., L.A. Mitchell, G. Stracquadanio, K. Yang, J.S. Dymond, J.E. DiCarlo, D. Lee, C.L. Huang, S. Chandrasegaran, Y. Cai, J.D. Boeke and J.S. Bader (2017). "Design of a synthetic yeast genome." Science 355(6329): 1040-1044.

Molina, O., N. Kouprina, H. Masumoto, V. Larionov and W.C. Earnshaw (2017). “Using human artificial chromosomes to study centromere assembly and function”.  Chromosoma 126:559-575.

Rata, S., M.F. Suarez Peredo Rodriguez, S. Joseph, N. Peter, F.E. Iturra, F. Yang, A. Madzvamuse, J.G. Ruppert, K. Samejima, M. Platani, M. Alvarez-Fernandez, M. Malumbres, W.C. Earnshaw, B. Novak & H. Hochegger. (2018). “Two interlinked bistable switches govern mitotic control in mammalian cells”.  Curr Biol 28: 3824–3832.

                                                    

Rizzotto, A. and E.C. Schirmer (2017). "Breaking the scale: how disrupting the karyoplasmic ratio gives cancer cells an advantage for metastatic invasion." Biochem Soc Trans 45(6): 1333-1344.

Robson, M.I., J.I. de Las Heras, R. Czapiewski, A. Sivakumar, A.R.W. Kerr and E.C. Schirmer (2017). "Constrained release of lamina-associated enhancers and genes from the nuclear envelope during T-cell activation facilitates their association in chromosome compartments." Genome Res 27(7): 1126-1138.

Robson, M.I., J.I. de las Heras, A.R.W. Kerr and E.C. Schirmer (2017). "Lymphocyte genes and an enhancer sequestered at the nuclear periphery undergo constrained release and associate upon T-cell activation." bioRxiv http://dx.doi.org/10.1101/062224.

Robson, M.I., A. Rizzotto and E.C. Schirmer (2018). "Spatial organization of the nucleus compartmentalizes and regulates the genome." In Nuclear Pore Complexes in Genome Organization, Function and Maintenance, ed. Maximillian D'Angelo. Springer, chpt. 1 (pp 1-34). ISBN 978-3-319-71612-1.

Romé, P. and H. Ohkura (2018) “A novel microtubule nucleation pathway for meiotic spindle assembly in oocytes”. J Cell Biol 217: 3431-3445.

Romé, P. and H. Ohkura (2018). "Combining microscopy and biochemistry to study meiotic spindle assembly in Drosophila oocytes."  Methods Cell Biol 145: 237-248.

Ruppert, J.G., K. Samejima, M. Platani, O. Molina, H. Kimura, A.A. Jeyaprakash, S. Ohta and W.C. Earnshaw (2018). "HP1alpha targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry." EMBO J 37(6).

Saiz-Ros, N., R. Czapiewski, A. Stevenson, I. Epifano, S.K. Swanson, M. McElwee, S. Vijayakrishnan, C.A. Richardson, C.R. Dixon, L. Pytowski, M.W. Goldberg, L. Florens, S.V. Graham and E.C. Schirmer (2017). "Host vesicle fusion proteins VAPB, Rab11b and Rab18 contribute to HSV-1 infectivity by facilitating egress through the nuclear membrane." bioRxiv http://dx.doi.org/10.1101/088633.

Saldivar, J.C., S. Hamperl, M.J. Bocek, M. Chung, T.E. Bass, F. Cisneros-Soberanis, K. Samejima, L. Xie, J.R. Paulson, W.C. Earnshaw, D. Cortez, T. Meyer and K.A. Cimprich. (2018). “An intrinsic S/G2 checkpoint enforced by ATR”.  Science 361: 806-810.

Samejima I. and W.C. Earnshaw. (2018). “Isolation of mitotic chromosomes from vertebrate cells and characterization of their proteome by mass spectrometry”. Methods Cell Biol 144: 329-348.

Samejima K., D. Booth, H. Ogawa, J. Paulson, L. Xie, C. Watson, M. Platani, M.T. Kanemaki and W.C. Earnshaw. (2018). “Functional analysis after rapid degradation of condensins and 3D-EM reveals chromatin volume is uncoupled from chromosome architecture in mitosis”. J Cell Science 131: pii jcs210187.

Sayou, C., G. Millan-Zambrano, H. Santos-Rosa, E. Petfalski, S. Robson, J. Houseley, T. Kouzarides and D. Tollervey (2017). "RNA Binding by Histone Methyltransferases Set1 and Set2." Mol Cell Biol 37(14).

Schneider, M., A. Belsom and J. Rappsilber (2018). "Protein tertiary structure by crosslinking/mass spectrometry". Trends Biochem Sci 43(3): 157-169.

Shchepachev, V., S. Bresson, C. Spanos, P. Petfalski, L. Fischer, J. Rappsilber, J. and D. Tollervey (2018). “Defining the RNA interactome by total RNA-associated protein purification”. bioRxiv, https://doi.org/10.1101/436253

Serikawa, T., C. Spanos, A. von Hacht, N. Budisa, J. Rappsilber and J. Kurreck (2018). "Comprehensive identification of proteins binding to RNA G-quadruplex motifs in the 5' UTR of tumor-associated mRNAs." Biochimie 144: 169-184.

Shah, R.R. and A.P. Bird (2017). "MeCP2 mutations: progress towards understanding and treating Rett syndrome." Genome Med 9(1): 17.

Shen, Y., Y. Wang, T. Chen, F. Gao, J. Gong, D. Abramczyk, R. Walker, H. Zhao, S. Chen, W. Liu, Y. Luo, C. A. Muller, A. Paul-Dubois-Taine, B. Alver, G. Stracquadanio, L.A. Mitchell, Z. Luo, Y. Fan, B. Zhou, B. Wen, F. Tan, Y. Wang, J. Zi, Z. Xie, B. Li, K. Yang, S.M. Richardson, H. Jiang, C.E. French, C.A. Nieduszynski, R. Koszul, A.L. Marston, Y. Yuan, J. Wang, J.S. Bader, J. Dai, J.D. Boeke, X. Xu, Y. Cai and H. Yang (2017). "Deep functional analysis of synII, a 770-kilobase synthetic yeast chromosome." Science 355(6329).

Shukla, M., P. Tong, S.A. White, P.P. Singh, A.M. Reid, S. Catania, A.L. Pidoux and R.C. Allshire (2018). "Centromeric DNA destabilizes H3 nucleosomes to promote CENP-A deposition during the cell cycle." Curr Biol 28:3924-3936.

Sivade Dumousseau, M., M. Koch, A. Shrivastava, D. Alonso-Lopez, J. De Las Rivas, N. Del-Toro, C. W. Combe, B. H. M. Meldal, J. Heimbach, J. Rappsilber, J. Sullivan, Y. Yehudi and S. Orchard (2018). "JAMI: a Java library for molecular interactions and data interoperability." BMC Bioinformatics 19(1): 133.

Spiller, F., B. Medina-Pritchard, M.A. Abad, M.A. Wear, O. Molina, W.C. Earnshaw and A.A. Jeyaprakash (2017). "Molecular basis for Cdk1-regulated timing of Mis18 complex assembly and CENP-A deposition." EMBO Rep 18(6): 894-905.  Doi:10.15252/embr.201643564.

Sy, B., J. Wong, S. Granneman, D. Tollervey, D. Gally and J.J. Tree (2018). "High-resolution, high-throughput analysis of Hfq-binding sites using UV crosslinking and analysis of cDNA (CRAC)." Methods Mol Biol 1737: 251-272.

Tay, Y. D., M. Leda, C. Spanos, J. Rappsilber, A.B. Goryachev and K.E. Sawin (2019). "Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex." Cell Rep 26(6): 1654-1667 e1657.

Tay, Y.D., M. Leda, A.B. Goryachev and K.E. Sawin (2018). "Local and global Cdc42 guanine nucleotide exchange factors for fission yeast cell polarity are coordinated by microtubules and the Tea1-Tea4-Pom1 axis." J Cell Sci 131(14).

Tillotson, R., J. Selfridge, M.V. Koerner, K.K.E. Gadalla, J. Guy, D. De Sousa, R.D. Hector, S.R. Cobb and A. Bird (2017). "Radically truncated MeCP2 rescues Rett syndrome-like neurological defects." Nature 550(7676): 398-401.

Tong, P., A.L. Pidoux, N.R.T. Toda, R. Ard, H. Berger, M. Shukla, J. Torres-Garcia, J. Mueller, C.A. Nieduszynski, and R.C. Allshire (2019) “Inter-species conservation of organisation and function between non-homologous regional centromeres. Nature Commun. (accepted in principle 28Jan19). Preprint available: bioRxiv doi: https://doi.org/10.1101/309815

Saiz-Ros, N., R. Czapiewski, I. Epifano, A. Stevenson, S.K. Swanson, C.R. Dixon, D.B. Zamora, M. McElwee, S. Vijayakrishnan, C.A. Richardson, L. Dong, D.A. Kelly, L. Pytowski, M.W. Goldberg, L. Florens, S.V. Graham and E.C. Schirmer (2019). "Host vesicle fusion protein VAPB contributes to the nuclear egress stage of Herpes Simplex Virus type-1 (HSV-1) replication." Cells 8(2).

Sivakumar, A., J.I. de las Heras and E.C. Schirmer (2019) Spatial genome organization: from development to disease. Front. Genet. In press.

Skourti-Stathaki, K., E. Torlai Triglia, M. Warburton, P. Voigt, A. Bird and A. Pombo (2019). “R-Loops Enhance Polycomb Repression at a Subset of Developmental Regulator Genes”. Mol. Cell epub doi: 10.1016/j.molcel.2018.12.016.

Stafford, J.M., C.-H Lee, P. Voigt, N. Descostes, R. Saldaña-Meyer, J.-R Yu, G. Leroy, O. Oksuz, J.R. Chapman, Suarez, F., et al. (2018). Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma. Science Advances 2018; 4:eaau5935.

Sy, B., J. Wong, S. Granneman, D. Tollervey, D. Gally and J.J. Tree (2018). "High-resolution, high-throughput analysis of Hfq-binding sites using UV crosslinking and analysis of cDNA (CRAC)." Methods Mol Biol 1737: 251-272.

Trubitsyna, M., G. Michlewski, D.J. Finnegan, A. Elfick, S.J. Rosser, J.M. Richardson and C.E. French (2017). "Use of mariner transposases for one-step delivery and integration of DNA in prokaryotes and eukaryotes by transfection." Nucleic Acids Res. 45(10): e89

Vargiu, G., A.A. Makarov, J. Allan, T. Fukagawa, D.G. Booth and W.C. Earnshaw (2017). "Stepwise unfolding supports a subunit model for vertebrate kinetochores." Proc Natl Acad Sci USA 114(12): 3133-3138.

Vasiliauskaitė, L., R.V. Berrens, I. Ivanova, C. Carrieri, W. Reik, A.J. Enright, and D. O'Carroll (2018). “Defective germline reprogramming rewires the spermatogonial transcriptome”. Nat Struct Mol Biol. 25(5): 394-404.

Vasiliauskaite, L., D. Vitsios, R.V. Berrens, C. Carrieri, W. Reik, A.J. Enright and D. O'Carroll (2017). "A MILI-independent piRNA biogenesis pathway empowers partial germline reprogramming." Nat Struct Mol Biol 24(7): 604-606.

Vizcaino, J.A., G. Mayer, S. Perkins, H. Barsnes, M. Vaudel, Y. Perez-Riverol, T. Ternent, J. Uszkoreit, M. Eisenacher, L. Fischer, J. Rappsilber, E. Netz, M. Walzer, O. Kohlbacher, A. Leitner, R.J. Chalkley, F. Ghali, S. Martinez-Bartolome, E.W. Deutsch and A.R. Jones (2017). "The mzIdentML Data Standard Version 1.2, Supporting Advances in Proteome Informatics." Mol Cell Proteomics 16(7): 1275-1285.

Wallace, E.W.J. and J.D. Beggs (2017). "Extremely fast and incredibly close: cotranscriptional splicing in budding yeast." RNA 23(5): 601-610.

Wang, D., S.P. McAteer, A.B. Wawszczyk, C.D. Russell, A. Tahoun, A. Elmi, S.L. Cockroft, D. Tollervey, S. Granneman, J.J. Tree and D.L. Gally (2018). "An RNA-dependent mechanism for transient expression of bacterial translocation filaments." Nucleic Acids Res. 46: 3366-3381. PMID: PMC5909449

Wasserman, G.A., A.D. Szymaniak, A.C. Hinds, K. Yamamoto, H. Kamata, N.M. Smith, K.L. Hilliard, C. Carrieri, A.T. Labadorf, L.J. Quinton, X. Ai, X. Varelas, F. Chen, J.P. Mizgerd, A. Fine, D. O'Carroll and M.R. Jones (2017). “Expression of Piwi proein MIWI2 defines a distinct population of multiciliated cells”. J Clin Invest.127(10):3866-3876.

Waters, S.A., S.P. McAteer, G. Kudla, I. Pang, N.P. Deshpande, T.G. Amos, K.W. Leong, M.R. Wilkins, R. Strugnell, D.L. Gally, D. Tollervey and J.J. Tree (2017). "Small RNA interactome of pathogenic E. coli revealed through crosslinking of RNase E". EMBO J 36(3): 374-387.

Wear, M.A., M.W. Nowicki, E.A. Blackburn, I.W. McNae and M.D. Walkinshaw (2017). "Thermo-kinetic analysis space expansion for cyclophilin-ligand interactions - identification of a new nonpeptide inhibitor using Biacore T200." FEBS Open Bio 7(4): 533-549.

Welburn, J.P.I. and C. Friel (2018). “Part list for a microtubule depolymerizing kinesin”. Biochemical Society Transactions. PMID:30467119

Welburn, J.P.I. and A.A. Jeyaprakash (2018). "Mechanisms of Mitotic Kinase Regulation: A Structural Perspective." Front Cell Dev Biol 6: 6. Doi:10.3389/fcell.2018.00006.

Wilson, M.D. and D. Durocher (2017). “Reading chromatin signatures after DNA double-strand breaks”. Philos Trans R Soc Lond B Biol Sci 372.

Wilson, M.D. and A. Costa, A. (2017). “Cryo-electron microscopy of chromatin biology”. Acta Crystallogr D Struct Biol 73: 541-548.

Winz, M.L., L. Peil, T.W. Turowski, J. Rappsilber and D. Tollervey (2019). "Molecular interactions between Hel2 and RNA supporting ribosome-associated quality control." Nat Commun 10(1): 563.

Wu, Y., B.Z. Li, M. Zhao, L.A. Mitchell, Z.X. Xie, Q.H. Lin, X. Wang, W.H. Xiao, Y. Wang, X. Zhou, H. Liu, X. Li, M.Z. Ding, D. Liu, L. Zhang, B.L. Liu, X.L. Wu, F.F. Li, X.T. Dong, Y. Cai et al (2017). "Bug mapping and fitness testing of chemically synthesized chromosome X." Science 355(6329).

Xie, Z.X., B.Z. Li, L.A. Mitchell, Y. Wu, X. Qi, Z. Jin, B. Jia, X. Wang, B. X. Zeng, H. M. Liu, Y, Cai et al (2017). "Perfect" designer chromosome V and behavior of a ring derivative." Science 355(6329).

Yadav, R.K., C.M. Jablonowski, A.G. Fernandez, B.R. Lowe, R.A. Henry, D. Finkelstein, K. J. Barnum, A.L. Pidoux, Y.M. Kuo, J. Huang, M.J. O'Connell, A.J. Andrews, A. Onar-Thomas, R.C. Allshire and J.F. Partridge (2017). "Histone H3G34R mutation causes replication stress, homologous recombination defects and genomic instability in S. pombe." Elife 6, pii: e27406.

Yoshikawa, H., Larance, M., Harney D.J., Sundaramoorthy, R., Ly, T., Owen-Hughes, T., Lamond, A.I. (2018). “Efficient analysis of mammalian polysomes in cells and tissues using Ribo Mega-SEC”. eLife 7: e36530.

Yuan, M., M.G. Vasquez-Valdivieso, I.W. McNae, P.A.M. Michels, L.A. Fothergill-Gilmore and M.D. Walkinshaw (2017). "Structures of Leishmania Fructose-1,6-Bisphosphatase Reveal Species-Specific Differences in the Mechanism of Allosteric Inhibition." J Mol Biol 429(20): 3075-3089.

Yuan, Z., A. Riera, L. Bai, J. Sun, S. Nandi, C. Spanos, Z. A. Chen, M. Barbon, J. Rappsilber, B. Stillman, C. Speck and H. Li (2017). "Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1." Nat Struct Mol Biol 24(3): 316-324.

Zhang, W., G. Zhao, Z. Luo, Y. Lin, L. Wang, Y. Guo, A. Wang, S. Jiang, Q. Jiang, J. Gong, Y. Wang, S. Hou, J. Huang, T. Li, Y. Qin, J. Dong, Q. Qin, J. Zhang, X. Zou, X. He, L. Zhao, Y. Xiao, M. Xu, E. Cheng, N. Huang, T. Zhou, Y. Shen, R. Walker, Y. Luo, Z. Kuang, L.A. Mitchell, K. Yang, S.M. Richardson, Y. Wu, B.Z. Li, Y.J. Yuan, H. Yang, J. Lin, G.Q. Chen, Q. Wu, J.S. Bader, Y. Cai, J.D. Boeke and J. Dai (2017). "Engineering the ribosomal DNA in a megabase synthetic chromosome." Science 355(6329).

Zhiteneva, A., J.J. Bonfiglio, A. Makarov, T. Colby, P. Vagnarelli, E.C. Schirmer, I. Matic and W.C. Earnshaw (2017). "Mitotic post-translational modifications of histones promote chromatin compaction in vitro." Open Biol 7(9).

Zhong, W., L. Cui, B.C. Goh, Q. Cai, P. Ho, Y.H. Chionh, M. Yuan, A.E. Sahili, L.A. Fothergill-Gilmore, M.D. Walkinshaw, J. Lescar and P.C. Dedon (2017). "Allosteric pyruvate kinase-based "logic gate" synergistically senses energy and sugar levels in Mycobacterium tuberculosis." Nat Commun 8(1): 1986.

Zuccotti, D., T. Tebaldi,, P. Peroni, M. Kohn, L. Gasperini, V. Potrich, V. Bonazza, T. Dudnakova, A. Rossi, G. Sanguinetti, L. Conti, P. Macchi, V. D'Agostino, G. Viero, D. Tollervey, S. Huttelmaier and A. Quattrone (2018). "HuD Is a neural translation enhancer acting on mTORC1-responsive genes and counteracted by the Y3 small non-coding RNA." Mol Cell 71(2): 256-270 e210.