Centre Publications 2017 - 2019

Agnieszka Tudek, A., M. Schmid, M. Makaras, J.D. Barrass, J.D., Beggs, and T. Heick Jensen (2018). “A nuclear export block triggers the decay of newly synthesized polyadenylated RNA”. Cell Reports, 24, 2457-2467, doi: 10.1016/j.celrep.2018.07.103

Agmon, N., Z. Tang, K. Yang, B. Sutter, S. Ikushima, Y. Cai, K. Caravelli, J.A. Martin, X. Sun, W.J. Choi, A. Zhang, G. Stracquadanio, H. Hao, B.P. Tu, D. Fenyo, J.S. Bader and J.D. Boeke (2017). "Low escape-rate genome safeguards with minimal molecular perturbation of Saccharomyces cerevisiae." Proc Natl Acad Sci U S A 114(8): E1470-E1479.

Allshire, R.C. and H.D. Madhani (2018). "Ten principles of heterochromatin formation and function”. Nat Rev Mol Cell Biol 19(4): 229-244.

Anedchenko, E.A., A. Samel-Pommerencke, T.M. Tran Nguyen, S. Shahnejat-Bushehri, J. Popsel, D. Lauster, A. Herrmann, J. Rappsilber, A. Cuomo, T. Bonaldi and A.E. Ehrenhofer-Murray (2019). "The kinetochore module Okp1(CENP-Q)/Ame1(CENP-U) is a reader for N-terminal modifications on the centromeric histone Cse4(CENP-A)”. EMBO J 38(1).

Anselm, E., A.W. Thomae, A.A. Jeyaprakash and P. Heun (2018). “Oligomerisation of Drosophila Nucleophosmin-like protein is required for its centromere localisation”. Nucleic Acid Res 46: 11274-11286.

Antequera, F. and A. Bird (2018). "CpG Islands: A Historical Perspective." Methods Mol Biol 1766: 3-13.

Ard, R., R.C. Allshire and S. Marquardt (2017). "Emerging properties and functional consequences of noncoding transcription." Genetics 207(2): 357-367.

Aslanzadeh, V., Y. Huang, G. Sanguinetti and J.D. Beggs (2018). "Transcription rate strongly affects splicing fidelity and cotranscriptionality in budding yeast." Genome Res 28(2): 203-213.

Ballarino, M., A. Cipriano, R. Tita, T. Santini, F. Desideri, M. Morlando, A. Colantoni, C. Carrieri, C. Nicoletti, A. Musarò, D. O’Carroll and I. Bozzoni (2018). “Deficiency in the nuclear long noncoding RNA Charme causes myogenic defects and heart remodeling in mice”. EMBO 37(18). pii: e99697. doi: 10.15252/embj.201899697. Epub 2018 Sep 3. PubMed PMID: 30177572.

Bao, X.X., C. Spanos, T. Kojidani, E.M. Lynch, J. Rappsilber, Y. Hiraoka, T. Haraguchi and K.E. Sawin (2018). "Exportin Crm1 is repurposed as a docking protein to generate microtubule organizing centers at the nuclear pore." Elife 7.

Barrey, E.J. and Heun, P. (2017). “Artificial chromosomes and strategies to initiate epigenetic centromere establishment”. Prog Mol Subcell Biol 56: 193-212.

Beaven, R., R.N. Bastos, C. Spanos, P. Rome, C.F. Cullen, J. Rappsilber, R. Giet, G. Goshima and H. Ohkura (2017). "14-3-3 regulation of Ncd reveals a new mechanism for targeting proteins to the spindle in oocytes." J Cell Biol 216(10): 3029-3039.

Beggs, J.D. (2017). "Pre-mRNA Splicing." In Reference Module in Life Sciences, Elsevier, 2017, ISBN: 978-0-12-809633-8, http://dx.doi.org/10.1016/B978-0-12-809633-8.06947-8.

Belsom, A., G. Mudd, S. Giese, M. Auer and J. Rappsilber (2017). "Complementary Benzophenone Cross-Linking/Mass Spectrometry Photochemistry." Anal Chem 89(10): 5319-5324.

Bharathavikru, R., T. Dudnakova, S. Aitken, J. Slight, M. Artibani, P. Hohenstein, D. Tollervey and N. Hastie (2017). "Transcription factor Wilms' tumor 1 regulates developmental RNAs through 3' UTR interaction." Genes Dev 31(4): 347-352.

Bikkul, M.U., R.G.A. Faragher, G. Worthington, P. Meinke, A.R.W. Kerr, A. Sammy, K. Riyahi, D. Horton, E.C. Schirmer, M. Hubank, I.R. Kill, R.M. Anderson, P. Slijepcevic, E. Makarov and J.M. Bridger (2018). "Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson-Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform." Genes Chromosomes Cancer doi: 10.1002/gcc.22711. PMID:30474255

Bird, A. (2017). "Genetic determinants of the epigenome in development and cancer." Swiss Med Wkly 147: w14523.

Bitetti, A., A.C. Mallory, E. Golini, C. Carrieri,  H. Carreño Gutiérrez, E. Perlas, Y.A. Pérez-Rico, G.P. Tocchini-Valentini, A.J. Enright, W.H.J. Norton, S. Mandillo, D. O'Carroll, and A. Shkumatava (2018). “MicroRNA degradation by a conserved target RNA regulates animal behaviour”. Nat Struct Mol Biol. 25(3):244-251.

Blyth, J., V. Makrantoni, R.E. Barton, C. Spanos, J. Rappsilber and A.L. Marston (2018). "Genes important for Schizosaccharomyces pombe meiosis identified through a functional genomics screen." Genetics 208(2): 589-603.

Bobkov, G.O.M., N. Gilbert and P. Heun (2018). "Centromere transcription allows CENP-A to transit from chromatin association to stable incorporation." J Cell Biol 217: 1957-1972.

Booth, D.G. and W.C. Earnshaw (2017). "Ki-67 and the chromosome periphery compartment in mitosis." Trends Cell Biol 27(12): 906-916.

Borek, W. and A.L. Marston (2018). “Diverse model systems reveal common principles of meiosis”. Genome Biology 19: 134.

Bresson, S. and D. Tollervey (2018). "Surveillance-ready transcription: nuclear RNA decay as a default fate." Open Biol 8(3).

Bresson, S., A. Tuck, D. Staneva and D. Tollervey (2017). "Nuclear RNA decay pathways aid rapid remodeling of gene expression in yeast." Mol Cell 65(5): 787-800 e785.

Bresson, S. and D. Tollervey (2018). “Tailing off: PABP and CNOT generate cycles of mRNA deadenylation”. Mol. Cell, 70: 987–988. PMID: 29932908.

Burmann, F., B.G. Lee, T. Than, L. Sinn, F.J. O'Reilly, S. Yatskevich, J. Rappsilber, B. Hu, K. Nasmyth and J. Lowe (2019). "A folded conformation of MukBEF and cohesin." Nat Struct Mol Biol 26(3): 227-236.

Cai, Y. and J. Dai (2017). "Methods to synthesize large DNA fragments for a synthetic yeast genome." Cold Spring Harb Protoc 2017(3): pdb prot080978.

Capitanchik, C., C. Dixon, S.K. Swanson, L. Florens, A.R.W. Kerr and E.C. Schirmer (2018). “Analysis of RNA-Seq datasets reveals enrichment of tissue-specific splice variants for nuclear envelope proteins”.  Nucleus 9(1), 410-430. PMID:29912636.

Carpy, A., A. Koch, C.C. Bicho, W.E. Borek, S. Hauf, K.E. Sawin and B. Macek (2017). "Stable isotope labeling by amino acids in cell culture (SILAC)-based quantitative proteomics and phosphoproteomics in fission yeast." Cold Spring Harb Protoc (6): pdb prot091686.

Carrieri, C., S. Comazzetto, A. Grover, M. Morgan, A. Buness, C. Nerlov and D. O'Carroll (2017). "A transit-amplifying population underpins the efficient regenerative capacity of the testis." J Exp Med 214(6): 1631-1641.

Cheerambathur, D.K., B. Prevo, T-L. Chow, N. Hattersley, S. Wang, Z. Zhao, T. Kim, A. Gerson-Gurwitz, K. Oegema, R. Green, R., et al. (2019). The kinetochore-microtubule coupling machinery Is repurposed in sensory nervous system morphogenesis. Dev. Cell.

Chen, J.W.C., A.A. Chen, K.B. Rogala, J. Metz, C.M. Deane, J. Rappsilber, and J.G. Wakefield (2017). “Cross-linking mass spectrometry identifies new interfaces of Augmin required to localise the γ-tubulin ring complex to the mitotic spindle”. Biol. Open 6: 654–663.

Chen, Z.A. and J. Rappsilber (2018). "Protein dynamics in solution by quantitative crosslinking/mass spectrometry." Trends Biochem Sci 43(11): 908-920.

Chen, Z.A. and J. Rappsilber (2019). "Quantitative cross-linking/mass spectrometry to elucidate structural changes in proteins and their complexes." Nat Protoc 14(1): 171-201.

Choudhury, N.R., G. Heikel, M. Trubitsyna, P. Kubik, J.S. Nowak, S. Webb, S. Granneman, C. Spanos, J. Rappsilber, A. Castello and G. Michlewski (2017). "RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination." BMC Biol 15(1): 105.

Combe, C.W., M.D. Sivade, H. Hermjakob, J. Heimbach, B.H.M. Meldal, G. Micklem, S. Orchard and J. Rappsilber (2017). "ComplexViewer: visualization of curated macromolecular complexes." Bioinformatics 33(22): 3673-3675.

Combes G., H. Barysz, C. Garand, L. Gama Braga, I. Alharbi, P. Thebault, L. Murakami, D.P. Bryne, S. Stankovic, P.A. Eyers, V.M. Bolanos-Garcia, W.C. Earnshaw, J. Maciejowski, P.V. Jallepalli and S. Elowe. (2018). “Mps1 phosphorylates its N-terminal extension to relieve autoinhibition and activate the spindle assembly checkpoint”. Curr Biol. 28: 872-883.

Crozier, T.W.M., M. Tinti, R.J. Wheeler, T. Ly, M.A.J. Ferguson and A.I. Lamond (2018). "Proteomic analysis of the cell cycle of procylic form Trypanosoma brucei." Mol. Cell. Proteomics 17: 1184-1195.

Cruz, M., M.A, Abad, W. van Ijcken, N. Galjart, A.A. Jeyaprakash, H. Maiato, and C. Ferrás (2018). Mitotic progression, arrest, exit or death is determined by centromere integrity and independent of de novo transcription. eLife 7:e36898 DOI: 10.7554/elLife.36898

Davis, M.P., C. Carrieri, H.K. Saini, S. van Dongen, T. Leonardi, G. Bussotti, J.M. Monahan, T. Auchynnikava, A. Bitetti, J. Rappsilber, R.C. Allshire, A. Shkumatava, D. O'Carroll and A.J. Enright (2017). "Transposon-driven transcription is a conserved feature of vertebrate spermatogenesis and transcript evolution." EMBO Rep 18(7): 1231-1247.

Dau, T., K. Gupta, I. Berger and J. Rappsilber (2019). "Sequential digestion with trypsin and elastase in cross-linking mass spectrometry." Anal Chem.

de Castro, I.J., J. Budzak, M.L. Di Giacinto, L. Ligammari, E. Gokhan, C. Spanos, D. Moralli, C. Richardson, J.I. de Las Heras, S. Salatino, E.C. Schirmer, K.S. Ullman, W.A. Bickmore, C. Green, J. Rappsilber, S. Lamble, M.W. Goldberg, V. Vinciotti and P. Vagnarelli (2017). "Repo-Man/PP1 regulates heterochromatin formation in interphase." Nat Commun 8: 14048.

de Las Heras, J.I., N. Zuleger, D.G. Batrakou, R. Czapiewski, A.R. Kerr and E.C. Schirmer (2017). "Tissue-specific NETs alter genome organization and regulation even in a heterologous system." Nucleus 8(1): 81-97.

de la Roche, M., D. Hamilton, R. Mortensen, A.A. Jeyaprakash, S. Gosh, and P.K. Anand (2018). Trafficking of cholesterol to the ER is required for NLRP3 inflammasome activation. J Cell Biol DOI: 10.1083/jcb.201709057.

Delan-Forino, C., C. Schneider and D. Tollervey (2017) Transcriptome-wide analysis of alternative routes for RNA substrates into the exosome complex. PLoS Gen. 13, e1006699. PMCID:PMC5389853

Delan-Forino, C., C. Schneider and D. Tollervey (2017). "RNA substrate length as an indicator of exosome interactions in vivo." Wellcome Open Res 2: 34.

Deretic J., A. Kerr and J.P.I. Welburn (2019). “A rapid computational approach identifies SPICE1 as an Aurora kinase substrate”. MBOC (30):312-323. PMID: 3048516.

Dixon, C.R. and E.C. Schirmer (2018). “Navigating the nuclear envelope: one or multiple transport mechanisms for integral membrane proteins?” In Nuclear-cytoplasmic transport from Springer Nucleic Acids and Molecular Biology series Vol 33, ed. Maximillian D'Angelo. Springer, chpt. 7 (pp 151-178). ISBN 978-3-319-77308-7.

Dixon, C.R., M. Platani, A.A. Makarov and E.C. Schirmer (2017). "Microinjection of antibodies targeting the lamin A/C histone-binding site blocks mitotic entry and reveals separate chromatin interactions with HP1, CenpB and PML." Cells 6(2).

Downie Ruiz Velasco, A., S.M.J. Welten, E.A.C. Goossens, P.H.A. Quax, J. Rappsilber, G. Michlewski and A.Y. Nossent (2019). "Posttranscriptional regulation of 14q32 MicroRNAs by the CIRBP and HADHB during vascular regeneration after ischemia." Mol Ther Nucleic Acids 14: 329-338.

Dudnakova, T., H. Dunn-Davies, R. Peters and D. Tollervey (2018). “Mapping targets for small nucleolar RNAs in yeast”. Wellcome Open Res. 3: 120. doi:10.12688/wellcomeopenres.14735.1

El Hage, A. and D. Tollervey (2018). "Immunoprecipitation of RNA:DNA hybrids from budding yeast." Methods Mol Biol 1703: 109-129.

Fischer, L. and J. Rappsilber (2018). "False discovery rate estimation and heterobifunctional cross-linkers." PLoS One 13(5): e0196672.

Fischer, L. and J. Rappsilber (2017). "Quirks of error estimation in cross-linking/mass spectrometry." Anal Chem 89(7): 3829-3833.

Fox, C., J. Zou, J. Rappsilber and A.L. Marston (2017). "Cdc14 phosphatase directs centrosome re-duplication at the meiosis I to meiosis II transition in budding yeast." Wellcome Open Res 2: 2.

Galander, S., R.E. Barton, D.A. Kelly and A.L. Marston (2019). “Spo13 prevents premature cohesin cleavage during meiosis” [version 1; referees: 1 approved with reservations]. Wellcome Open Res 4: 29.

Gatticchi, L., J.I. de las Heras, R. Roberti and E.C. Schirmer (2018). “Optimization of DamID for use in primary cultures of mouse hepatocytes”. Methods pii: S1046-2023(18)30119-1. PMID:30445179.

Gautam, A. and J.D. Beggs (2019). “Mutagenesis of Snu114 domain IV identifies a developmental role in meiotic splicing”. RNA Biology 16: 185–195. doi: 10.1080/15476286.2018.1561145

Georgiou, C., I. McNae, M. Wear, H. Ioannidis, J. Michel and M. Walkinshaw (2017). "Pushing the limits of detection of weak binding using fragment-based drug discovery: identification of new cyclophilin binders." J Mol Biol 429(16): 2556-2570.

Gerboth, S., E. Frittoli, A. Palamidessi, F.C. Baltanas, M. Salek, J. Rappsilber, C. Giuliani, F. Troglio, Y. Rolland, G. Pruneri, S. Kreutmair, I. Pallavicini, M. Zobel, M. Cinquanta, S. Minucci, C. Gomez, E. Santos, A.L. Illert and G. Scita (2018). "Phosphorylation of SOS1 on tyrosine 1196 promotes its RAC GEF activity and contributes to BCR-ABL leukemogenesis." Leukemia 32(3): 820-827.

Gibcus, J.H., K. Samejima, A. Goloborodko, I. Samejima, N. Naumova, J. Nuebler, M.T. Kanemaki, L. Xie, J.R. Paulson, W.C. Earnshaw, L.A. Mirny and J. Dekker (2018). "A pathway for mitotic chromosome formation." Science 9:359(6376).

Giese, S.H., A. Belsom and J. Rappsilber (2017). "Correction to optimized fragmentation regime for diazirine photo-cross-linked peptides." Anal Chem 89(6): 3802-3803.

Gigant, E., M. Stefanutti, K. Laband, A. Gluszek-Kustusz, F. Edwards, B. Lacroix, G. Maton, J.C. Canman, J.P.I. Welburn and J. Dumont (2017). "Inhibition of ectopic microtubule assembly by the kinesin-13 KLP-7 prevents chromosome segregation and cytokinesis defects in oocytes." Development 144(9): 1674-1686.

Giotti, B., S. Chen, M.W. Barnett, T. Regan, T. Ly, S. Wiemann, D.A. Hume and T. Freeman (2018). "Assembly of a parts list of the human mitotic cell cycle machinery." J Mol Cell Biol mjy063, https://doi.org/10.1093/jmcb/mjy063.

Guitart, A.V., T.I. Panagopoulou, A. Villacreces, M. Vukovic, C. Sepulveda, L. Allen, R.N. Carter, L. N. van de Lagemaat, M. Morgan, P. Giles, Z. Sas, M.V. Gonzalez, H. Lawson, J. Paris, J. Edwards-Hicks, K. Schaak, C. Subramani, D. Gezer, A. Armesilla-Diaz, J. Wills, A. Easterbrook, D. Coman, C.W. So, D. O'Carroll, D. Vernimmen, N.P. Rodrigues, P.J. Pollard, N.M. Morton, A. Finch and K.R. Kranc (2017). "Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions." J Exp Med 214(3): 719-735.

Gupta, K., A.A. Watson, T. Baptista, E. Scheer, A.L. Chambers, C. Koehler, J. Zou, I. Obong-Ebong, E. Kandiah, A. Temblador, A. Round, E. Forest, P. Man, C. Bieniossek, E.D. Laue, E.A. Lemke, J. Rappsilber, C.V. Robinson, D. Devys, L. Tora and I. Berger (2017). "Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID." Elife 6.

Guy, J., B. Alexander-Howden, L. FitzPatrick, D. DeSousa, M. V. Koerner, J. Selfridge and A. Bird (2018). "A mutation-led search for novel functional domains in MeCP2." Hum Mol Genet 27(14): 2531-2545.

Hegarat, N., A. Crncec, M.F. Rodriguez, F. Iturra, Y. Gu, P.F. Lang, A.R. Barr, C. Bakal,  M.T. Kanemaki, A.I. Lamond, B. Novak, T. Ly and H. Hochegger (2018). “Cyclin A triggers mitosis either via Greatwall or Cyclin B”. bioRxiv https://dx.doi.org/10.1101/501684.

Heyn, P., C.V. Logan, A. Fluteau, R.C. Challis,, T. Auchynnikava, C.A. Martin, J.A. Marsh, F. Taglini, F. Kilanowski, D.A. Parry, V. Cormier-Daire, C.T. Fong, K. Gibson, V. Hwa, L. Ibáñez, S.P. Robertson, G. Sebastiani, J. Rappsilber, R.C. Allshire, M.A.M. Reijns, A. Dauber, D. Sproul, A.P. Jackson (2019). “Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions”. Nat Genet. 51:96-105.

Hinshaw, S.M., V. Makrantoni, S.C. Harrison and A.L. Marston (2017). "The kinetochore receptor for the cohesin loading complex." Cell 171(1): 72-84 e13.

Ivanova, I., C. Much, M. Di Giacomo, C. Azzi, M. Morgan, P.N. Moreira, J. Monahan, C. Carrieri, A.J. Enright and D. O'Carroll (2017). "The RNA m(6)A Reader YTHDF2 is essential for the post-transcriptional regulation of the maternal transcriptome and oocyte competence." Mol Cell 67(6): 1059-1067 e1054.

Jacob, Y. and P. Voigt (2018). "In Vitro Assays to Measure Histone Methyltransferase Activity Using Different Chromatin Substrates." Methods Mol Biol 1675: 345-360.

Jantsch, M.F., A. Quattrone, M. O'Connell, M. Helm, M. Frye, M. Macias-Gonzales M, M. Ohman, S. Ameres, L. Willems, F. Fuks, A. Oulas, S. Vanacova, H. Nielsen, C. Bousquet-Antonelli C, Motorin Y, Roignant JY, Balatsos N, Dinnyes A, Baranov P,Kelly V, Lamm A, G. Rechavi, M. Pelizzola et al and D. O Carroll, J. Ule and R. Fray (2018) “Positioning Europe for the EPITRANSCRIPTOMICS challenge”. RNA Biol. 9:1-3. doi:10.1080/15476286.2018.1460996. [Epub ahead of print] PubMed PMID: 29671387.

Kastritis, P.L., F.J. O'Reilly, T. Bock, Y. Li, M.Z. Rogon, K. Buczak, N. Romanov, M.J. Betts, K.H. Bui, W.J. Hagen, M.L. Hennrich, M.T. Mackmull, J. Rappsilber, R.B. Russell, P. Bork, M. Beck and A.C. Gavin (2017). "Capturing protein communities by structural proteomics in a thermophilic eukaryote". Mol Syst Biol 13(7): 936.

Kitevski-LeBlanc, J., A. Fradet-Turcotte, P. Kukic, M.D. Wilson, G. Portella, T. Yuwen, S. Panier, S. Duan, M.D. Canny, H. van Ingen, C.H. Arrowsmith, J.L. Rubinstein, M. Vendruscolo, D. Durocher and L.E. Kay (2017). "The RNF168 paralog RNF169 Defines a new class of ubiquitylated histone reader involved in the response to DNA

damage". Elife 6.

Koch, A., C.C. Bicho, W.E. Borek, A. Carpy, B. Macek, S. Hauf and K.E. Sawin (2017). "Construction, growth, and harvesting of fission yeast stable isotope labeling by amino acids in cell culture (SILAC) strains." Cold Spring Harb Protoc (6): pdb prot091678.

Koerner, M.V., L. FitzPatrick, J. Selfridge, J. Guy, D. De Sousa, R. Tillotson, A. Kerr, Z. Sun, M.A. Lazar, M.J. Lyst and A. Bird (2018). "Toxicity of overexpressed MeCP2 is independent of HDAC3 activity". Genes Dev 32(23-24): 1514-1524.

Kolbowski, L., M.L. Mendes and J. Rappsilber (2017). "Optimizing the parameters governing the fragmentation of cross-linked peptides in a Tribrid mass spectrometer". Anal Chem 89(10): 5311-5318.

Kouprina N., N. Petrov, O. Molina, M. Liskovykh, E. Pesenti, J.I. Ohzeki, H. Masumoto, W.C. Earnshaw and V. Larionov. (2018). “Human artificial chromosome with regulated centromere: a tool for genome and cancer studies”.  ACS Synth Biol. 7: 1974-1989.

Kozlowski, E., G.A. Wasserman, M. Morgan, D. O'Carroll, N.P. Ramirez, S. Gummuluru, J.Y. Rah, A.C. Gower, M. Ieong, L.J. Quinton, J.P. Mizgerd and M.R. Jones (2017). "The RNA uridyltransferase Zcchc6 is expressed in macrophages and impacts innate immune responses." PLoS One 12(6): e0179797.

Kruusvee, V., M.J. Lyst, C. Taylor, Z. Tarnauskaite, A.P. Bird and A.G. Cook (2017). "Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders." Proc Natl Acad Sci USA 114(16): E3243-E3250.

Kulasegaran-Shylini, R., L. Subramanian, A.R.W. Kerr, C. Spanos, J. Rappsilber and R.C. Allshire (2018). "Swr1-mediated H2A.Z incorporation designates centromere DNA for de novo CENP-A assembly." bioRxiv [Nov 2017.

Kyriacou, E. and Heun, P. (2018). “High-resolution mapping of centromeric protein association using APEX-chromatin fibers”. Epigenetics Chromatin 11: 68.

Ladds, M., I.M.M. van Leeuwen, C.J. Drummond, S. Chu, A.R. Healy, G. Popova, A. Pastor Fernandez, T. Mollick, S. Darekar, S.K. Sedimbi, M. Nekulova, M.C.C. Sachweh, J. Campbell, M. Higgins, C. Tuck, M. Popa, M.M. Safont, P. Gelebart, Z. Fandalyuk, A.M. Thompson, R. Svensson, A.L. Gustavsson, L. Johansson, K. Farnegardh, U. Yngve, A. Saleh, M. Haraldsson, A.C.A. D'Hollander, M. Franco, Y. Zhao, M. Hakansson, B. Walse, K. Larsson, E. M. Peat, V. Pelechano, J. Lunec, B. Vojtesek, M. Carmena, W.C. Earnshaw A.R. McCarthy, N.J. Westwood, M. Arsenian-Henriksson, D.P. Lane, R. Bhatia, E. McCormack and S. Lain (2018). "A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage." Nat Commun 9(1): 1107.

Lagger, S., J.C. Connelly, G. Schweikert, S. Webb, J. Selfridge, B.H. Ramsahoye, M. Yu, C. He, G. Sanguinetti, L.C. Sowers, M.D. Walkinshaw and A. Bird (2017). "MeCP2 recognizes cytosine methylated tri-nucleotide and di-nucleotide sequences to tune transcription in the mammalian brain." PLoS Genet 13(5): e1006793.

Lee, N.C.O., J.H. Kim, N.S. Petrov, H.S. Lee, H. Masumoto, W.C. Earnshaw, V. Larionov and N. Kouprina (2018). "Method to assemble genomic DNA fragments or genes on human artificial chromosome with regulated kinetochore using a multi-integrase system." ACS Synth Biol 7(1): 63-74.

Lee, H.S., M. Carmena, M. Liskovykh, E. Peat, J.H. Kim, M. Oshimura, H. Masumoto, M.P. Teulade-Fichou, Y. Pommier, W.C. Earnshaw, V. Larionov and N. Kouprina (2018). Systematic analysis of compounds specifically targeting telomeres and telomerase for clinical implications in cancer therapy”.  Cancer Res 78: 6282-6296.

Lenz, S., S.H. Giese, L. Fischer and J. Rappsilber (2018). "In-search assignment of monoisotopic peaks improves the identification of cross-linked peptides." J Proteome Res 17(11): 3923-3931.

Le Pen J., H. Jiang, T. Di Domenico, E. Kneuss, J. Kosałka, C. Leung, M. Morgan, C. Much, K.L.M. Rudolph, A.J. Enright, D. O'Carroll, D. Wang, and E.A. Miska (2018). “Terminal uridylyltransferases target RNA viruses as part of the innate immune system”. Nat Struct Mol Biol. 25(9): 778-786. doi: 10.1038/s41594-018-0106-9. Epub 2018 Aug 13. PubMed PMID: 30104661.

Le Thanh, P., P. Meinke, N. Korfali, V. Srsen, M.I. Robson, M. Wehnert, B. Schoser, C.A. Sewry and E.C. Schirmer (2017). "Immunohistochemistry on a panel of Emery-Dreifuss muscular dystrophy samples reveals nuclear envelope proteins as inconsistent markers for pathology." Neuromuscul Disord 27(4): 338-351.

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