Centre Optical Instrumentation Laboratory (COIL)

COIL Manager: Dr David Kelly
Telephone +44 131 650 7525
Fax +44 131 650 7525

The COIL facility is funded by the Wellcome Trust through the Centre core grant and contains state-of-the-art imaging equipment which is managed and supported by the facility manager, David Kelly.  Equipment available in the facility includes Leica SP5 Confocal, Spinning Disk Confocal, GE Deltavision Elite, Zeiss LSM880 with Airyscan, BD FACS Analyser, Microinjector, Licor Odyssey.  All users must register with the COIL manager and undergo training before they are granted access to the equipment and the on-line booking site.

Information about COIL

Bioinformatics Core Facility

Bioinformatics Core Facility Manager: Shaun Webb
Telephone +44(0)131 650 7527

The Bioinformatics Core Facility is funded by the Wellcome Trust through the Centre core grant. The facility is managed by Shaun Webb supported by two experienced bioinformaticians: Hywel Dunn-Davies and Dan Robertson.  The Facility provides regular training sessions, tools, advice and data analysis services to Centre members. The bioinformatics wiki (editable web) page provides further information about the facility, training course materials and in-house programmes.

Bioinformatics wiki

Proteomics Facility

Proteomics Facility Manager: Dr Christos Spanos
Telephone +44 (0)131 650 7057

The Proteomics Facility is funded by the Wellcome Trust through the Centre core grant and is managed by Christos Spanos and supported by Dr. Juan Zou, with Professor Juri Rappsilber providing academic leadership. The Facility is equipped with highly advanced mass spectrometers including the Orbitrap Fusion Lumos, the Q Exactive and the Orbitrap Elite, all coupled to Ultimate 3000 RSLCnano Systems.  Shotgun proteomics for protein identification and post-translational modifications analysis, label and label-free quantification, crosslinking analysis as well as targeted analysis and DIA are available to the researchers. Training on a wide range of techniques and data analysis software platforms is provided through face-to-face interactions as well as through the annual proteomics course.   

Edinburgh Protein Production Facility (EPPF)

EPPF Manager: Dr Martin Wear
Telephone +44 (0)131 650 7054)

The Edinburgh Protein Production Facility provides core facilities for protein production and characterisation. Rapid solutions to the production of proteins and the biophysical chracterisation of their ligands underpins many of the important questions being asked in structural and translational biology today. The Wellcome Trust, SULSA and University of Edinburgh funded Protein Production Facility (EPPF) provides researchers with access to state-of-the-art equipment and excellent end-user core facilities to address these questions.

Information about the EPPF