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Centre Publications 2015 - 2017

Abad, M.A., J. Zou, B. Medina-Pritchard, E.A. Nigg, J. Rappsilber, A. Santamaria and A.A. Jeyaprakash (2016). Ska3 ensures timely mitotic progression by interacting directly with microtubules and Ska1 microtubule binding domain. Sci Rep 6: 34042.

 

Agirre, X., G. Castellano, M. Pascual, S. Heath, M. Kulis, V. Segura, A. Bergmann, A. Esteve, A. Merkel, E. Raineri, L. Agueda, J. Blanc, D. Richardson, L. Clarke, A. Datta, N. Russinol, A.C. Queiros, R. Beekman, J.R. Rodriguez-Madoz, E.S. Jose-Eneriz, F. Fang, N.C. Gutierrez, J.M. Garcia-Verdugo, M.I. Robson, E.C. Schirmer, et al (2015). Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers. Genome Res 25: 478-487.

 

Agmon, N., Z. Tang, K. Yang, B. Sutter, S. Ikushima, Y. Cai, K. Caravelli, J.A. Martin, X. Sun, W.J. Choi, A. Zhang, G. Stracquadanio, H. Hao, B.P. Tu, D. Fenyo, J.S. Bader and J.D. Boeke (2017). Low escape-rate genome safeguards with minimal molecular perturbation of Saccharomyces cerevisiae. Proc Natl Acad Sci USA 114(8): E1470-E1479.

 

Agmon, N., L.A. Mitchell, Y. Cai, S. Ikushima, J. Chuang, A. Zheng, W.J. Choi, J.A. Martin, K. Caravelli, G. Stracquadanio and J.D. Boeke (2015). Yeast Golden Gate (yGG) for the Efficient Assembly of S. cerevisiae Transcription Units. ACS Synth Biol 4(7): 853-859.

 

Allshire, R.C. and K. Ekwall (2015). Epigenetic Regulation of Chromatin States in Schizosaccharomyces pombe. Cold Spring Harb Perspect Biol 7(7): a018770.

 

Ard, R. and R.C. Allshire (2016). Transcription-coupled changes to chromatin underpin gene silencing by transcriptional interference. Nucleic Acids Res 44(22): 10619-10630.

 

Audergon, P.N., S. Catania, A. Kagansky, P. Tong, M. Shukla, A.L. Pidoux and R.C. Allshire (2015). Epigenetics. Restricted epigenetic inheritance of H3K9 methylation. Science 348(6230): 132-135.

 

Barrass, J.D., J.E. Reid, Y. Huang, R.D. Hector, G. Sanguinetti, J.D. Beggs and S. Granneman (2015). Transcriptome-wide RNA processing kinetics revealed using extremely short 4tU labeling. Genome Biol 16: 282.

 

Barysz, H., J.H. Kim, Z.A. Chen, D.F. Hudson, J. Rappsilber, D.L. Gerloff and W.C. Earnshaw (2015). Three-dimensional topology of the SMC2/SMC4 subcomplex from chicken condensin I revealed by cross-linking and molecular modelling. Open Biol 5(2): 150005.

 

Batrakou, D.G., J.I. de Las Heras, R. Czapiewski, R. Mouras and E.C. Schirmer (2015). TMEM120A and B: nuclear envelope transmembrane proteins important for adipocyte differentiation. PLoS One 10(5): e0127712.

 

Beaven, R., N.S. Dzhindzhev, Y. Qu, I. Hahn, F. Dajas-Bailador, H. Ohkura and A. Prokop (2015). Drosophila CLIP-190 and mammalian CLIP-170 display reduced microtubule plus end association in the nervous system. Mol Biol Cell 26: 1491-1508.

 

Belsom, A., M. Schneider, O. Brock and J. Rappsilber (2016). Blind evaluation of hybrid protein structure analysis methods based on cross-linking. Trends Biochem Sci 41(7): 564-567.

 

Belsom, A., M. Schneider, L. Fischer, O. Brock and J. Rappsilber (2016). Serum albumin domain structures in human blood serum by mass spectrometry and computational biology. Mol Cell Proteomics 15(3): 1105-1116.

 

Bharathavikru, R., T. Dudnakova, S. Aitken, J. Slight, M. Artibani, P. Hohenstein, D. Tollervey and N. Hastie (2017). Transcription factor, Wilms’ Tumour 1 regulates developmental RNAs through 3’ UTR interaction. Genes Dev in press.

 

Blackburn, E.A., M.A. Wear, V. Landre, V. Narayan, J. Ning, B. Erman, K.L. Ball and M.D. Walkinshaw (2015). Cyclophilin40 isomerase activity is regulated by a temperature-dependent allosteric interaction with Hsp90. Biosci Rep 35(5).

 

Boeke, J.D., G. Church, A. Hessel, N.J. Kelley, A. Arkin, Y. Cai, R. Carlson, A. Chakravarti, V.W. Cornish, L. Holt, F.J. Isaacs, T. Kuiken, M. Lajoie, T. Lessor, J. Lunshof, M.T. Maurano, L.A. Mitchell, J. Rine, S. Rosser, N.E. Sanjana, P.A. Silver, D. Valle, H. Wang, J.C. Way and L. Yang (2016). GENOME ENGINEERING. The Genome Project-Write. Science 353(6295): 126-127.

 

Booth, D.G., A.J. Beckett, O. Molina, I. Samejima, H. Masumoto, N. Kouprina, V. Larionov, I.A. Prior and W.C. Earnshaw (2016). 3D-CLEM Reveals that a Major Portion of Mitotic Chromosomes Is Not Chromatin. Mol Cell 64(4): 790-802.

 

Borek, W.E., L.M. Groocock, I. Samejima, J. Zou, F. de Lima Alves, J. Rappsilber and K.E. Sawin (2015). Mto2 multisite phosphorylation inactivates non-spindle microtubule nucleation complexes during mitosis. Nat Commun 6: 7929.

 

Borek, W.E., J. Zou, J. Rappsilber and K.E. Sawin (2015). Deletion of genes encoding arginase improves use of "heavy" isotope-labeled arginine for mass spectrometry in fission yeast. PLoS One 10(6): e0129548.

 

Botte, M., N.R. Zaccai, J.L. Nijeholt, R. Martin, K. Knoops, G. Papai, J. Zou, A. Deniaud, M. Karuppasamy, Q. Jiang, A.S. Roy, K. Schulten, P. Schultz, J. Rappsilber, G. Zaccai, I. Berger, I. Collinson and C. Schaffitzel (2016). A central cavity within the holo-translocon suggests a mechanism for membrane protein insertion. Sci Rep 6: 38399.

 

Bresson, S., A. Tuck, D. Staneva and D. Tollervey (2017). Nuclear RNA decay pathways aid rapid remodeling of gene expression in yeast. Mol Cell 65(5): 787-800 e785.

 

Breuer, M. and H. Ohkura (2015). A negative loop within the nuclear pore complex controls global chromatin organization. Genes Dev 29(17): 1789-1794.

 

Brewster, R.C., G.C. Gavins, B. Gunthardt, S. Farr, K.M. Webb, P. Voigt and A.N. Hulme (2016). Chloromethyl-triazole: a new motif for site-selective pseudo-acylation of proteins. Chem Commun (Camb) 52(82): 12230-12232.

 

Brown, K., J. Selfridge, S. Lagger, J. Connelly, D. De Sousa, A. Kerr, S. Webb, J. Guy, C. Merusi, M.V. Koerner and A. Bird (2016). The molecular basis of variable phenotypic severity among common missense mutations causing Rett syndrome. Hum Mol Genet 25(3): 558-570.

 

Cai, Y., N. Agmon, W.J. Choi, A. Ubide, G. Stracquadanio, K. Caravelli, H. Hao, J.S. Bader and J.D. Boeke (2015). Intrinsic biocontainment: multiplex genome safeguards combine transcriptional and recombinational control of essential yeast genes. Proc Natl Acad Sci USA 112(6): 1803-1808.

 

Cai, Y. and J. Dai (2017). Methods to Synthesize Large DNA Fragments for a Synthetic Yeast Genome. Cold Spring Harb Protoc 2017(3): pdb prot080978.

 

Capalbo, L., I. Mela, M.A. Abad, A.A. Jeyaprakash, J.M. Edwardson and P.P. D'Avino (2016). Coordinated regulation of the ESCRT-III component CHMP4C by the chromosomal passenger complex and centralspindlin during cytokinesis. Open Biol 6(10).

 

Carmena, M., W.C. Earnshaw and D.M. Glover (2015). The dawn of Aurora Kinase research: from fly genetics to the clinic. Front Cell Dev Biol 3: 73.

 

Castonguay, E., S.A. White, A. Kagansky, D.J. St-Cyr, A.G. Castillo, C. Brugger, R. White, C. Bonilla, M. Spitzer, W.C. Earnshaw, T. Schalch, K. Ekwall, M. Tyers and R.C. Allshire (2015). Panspecies small-molecule disruptors of heterochromatin-mediated transcriptional gene silencing. Mol Cell Biol 35(4): 662-674.

 

Catania, S., A.L. Pidoux and R.C. Allshire (2015). Sequence Features and Transcriptional Stalling within Centromere DNA Promote Establishment of CENP-A Chromatin. PLoS Genet 11(3): e1004986.

 

Chen, Z., L. Fischer, S. Tahir, J.C. Bukowski-Wills, P. Barlow and J. Rappsilber (2016). Quantitative cross-linking/mass spectrometry reveals subtle protein conformational changes. Wellcome Open Res 1: 5.

 

Chen, Z. A., L. Fischer, J. Cox and J. Rappsilber (2016). Quantitative cross-linking/mass spectrometry using isotope-labeled cross-linkers and MaxQuant. Mol Cell Proteomics 15(8): 2769-2778.

 

Chen, Z. A., R. Pellarin, L. Fischer, A. Sali, M. Nilges, P.N. Barlow and J. Rappsilber (2016). Structure of Complement C3(H2O) Revealed By Quantitative Cross-Linking/Mass Spectrometry And Modeling. Mol Cell Proteomics 15(8): 2730-2743.

 

Cholewa-Waclaw, J., A. Bird, M. von Schimmelmann, A. Schaefer, H. Yu, H. Song, R. Madabhushi and L.H. Tsai (2016). The Role of Epigenetic Mechanisms in the Regulation of Gene Expression in the Nervous System. J Neurosci 36(45): 11427-11434.

 

Combe, C.W., L. Fischer and J. Rappsilber (2015). xiNET: cross-link network maps with residue resolution. Mol Cell Proteomics 14(4): 1137-1147.

 

Cook, P.C., H. Owen, A.M. Deaton, J.G. Borger, S.L. Brown, T. Clouaire, G.R. Jones, L.H. Jones, R.J. Lundie, A.K. Marley, V.L. Morrison, A.T. Phythian-Adams, E. Wachter, L.M. Webb, T.E. Sutherland, G.D. Thomas, J.R. Grainger, J. Selfridge, A.N. McKenzie, J.E. Allen, S.C. Fagerholm, R.M. Maizels, A.C. Ivens, A. Bird and A.S. MacDonald (2015). A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells. Nat Commun 6: 6920.

                                                                

Czapiewski, R., M.I. Robson and E.C. Schirmer (2016). Anchoring a Leviathan: How the Nuclear Membrane Tethers the Genome. Front Genet 7: 82.

 

de Castro, I.J., J. Budzak, M.L. Di Giacinto, L. Ligammari, E. Gokhan, C. Spanos, D. Moralli, C. Richardson, J.I. de Las Heras, S. Salatino, E.C. Schirmer, K.S. Ullman, W.A. Bickmore, C. Green, J. Rappsilber, S. Lamble, M.W. Goldberg, V. Vinciotti and P. Vagnarelli (2017). Repo-Man/PP1 regulates heterochromatin formation in interphase. Nat Commun 8: 14048.

 

de Las Heras, J.I., N. Zuleger, D.G. Batrakou, R. Czapiewski, A.R. Kerr and E.C. Schirmer (2017). Tissue-specific NETs alter genome organization and regulation even in a heterologous system. Nucleus 8(1): 81-97.

 

Duro, E. and A.L. Marston (2015). From equator to pole: splitting chromosomes in mitosis and meiosis. Genes Dev 29(2): 109-122.

 

Earnshaw, W.C. (2015). Q&A. Curr Biol 25: R483-R489.

 

Earnshaw, W.C. (2015). Discovering centromere proteins: from cold white hands to the A, B, C of CENPs. Nat Rev Mol Cell Biol 16(7): 443-449.

 

Ellis, T. and Y. Cai (2016). Synthetic Biology in Europe. ACS Synth Biol 5(10): 1033.

 

Fernandes, P.M., J. Kinkead, I. McNae, P. Michels and M.D. Walkinshaw (2016). Biochemical and biophysical studies of Trypanosoma cruzi phosphofructokinase as a target against Chagas disease. The Lancet 387: S43.

 

Folco, H.D., C.S. Campbell, K.M. May, C.A. Espinoza, K. Oegema, K.G. Hardwick, S.I. Grewal and A. Desai (2015). The CENP-A N-tail confers epigenetic stability to centromeres via the CENP-T branch of the CCAN in fission yeast. Curr Biol 25(3): 348-356.

 

Fox, C., J. Zou, J. Rappsilber and A.L. Marston (2017). Cdc14 phosphatase directs centrosome re-duplication at the meiosis I to meiosis II transition in budding yeast. Wellcome Open Res 2: 2.

 

France, D.J., G. Stepek, D.R. Houston, L. Williams, G. McCormack, M.D. Walkinshaw and A.P. Page (2015). Identification and activity of inhibitors of the essential nematode-specific metalloprotease DPY-31. Bioorg Med Chem Lett 25(24): 5752-5755.

 

Fraser, J.A., E.G. Worrall, Y. Lin, V. Landre, S. Pettersson, E. Blackburn, M. Walkinshaw, P. Muller, B. Vojtesek, K. Ball and T.R. Hupp (2015). Phosphomimetic mutation of the N-terminal lid of MDM2 enhances the polyubiquitination of p53 through stimulation of E2-ubiquitin thioester hydrolysis. J Mol Biol 427(8): 1728-1747.

 

Gal, C., H.E. Murton, L. Subramanian, A.J. Whale, K.M. Moore, K. Paszkiewicz, S. Codlin, J. Bahler, K.M. Creamer, J.F. Partridge, R.C. Allshire, N.A. Kent and S.K. Whitehall (2016). Abo1, a conserved bromodomain AAA-ATPase, maintains global nucleosome occupancy and organisation. EMBO Rep 17(1): 79-93.

 

Gautam, A., R.J. Grainger, J. Vilardell, J.D. Barrass and J.D. Beggs (2015). Cwc21p promotes the second step conformation of the spliceosome and modulates 3' splice site selection. Nucleic Acids Res. 43: 3309-3317.

 

Giese, S.H., A. Belsom and J. Rappsilber (2016). Optimized fragmentation regime for diazirine photo-cross-linked peptides. Anal Chem 88(16): 8239-8247.

 

Giese, S.H., L. Fischer and J. Rappsilber (2016). A study into the Collision-Induced Dissociation (CID) behavior of cross-linked peptides. Mol Cell Proteomics 15(3): 1094-1104.

 

Gluszek, A.A., C.F. Cullen, W. Li, R.A. Battaglia, S.J. Radford, M. F. Costa, K. S. McKim, G. Goshima and H. Ohkura (2015). The microtubule catastrophe promoter Sentin delays stable kinetochore-microtubule attachment in oocytes. J Cell Biol 211(6): 1113-1120.

 

Gonzalez-Loyola, A., G. Fernandez-Miranda, M. Trakala, D. Partida, K. Samejima, H. Ogawa, M. Canamero, A. de Martino, A. Martinez-Ramirez, G. de Carcer, I. Perez de Castro, W.C. Earnshaw and M. Malumbres (2015). Aurora B overexpression causes aneuploidy and p21Cip1 repression during tumor development. Mol Cell Biol 35(20): 3566-3578.

 

Grunstein, M. and A. Bird (2015). Max Birnstiel 1933-2014: Gene pioneer. Proc Natl Acad Sci USA 112(2): 302-303.

 

Guo, Y., J. Dong, T. Zhou, J. Auxillos, T. Li, W. Zhang, L. Wang, Y. Shen, Y. Luo, Y. Zheng, J. Lin, G.Q. Chen, Q. Wu, Y. Cai and J. Dai (2015). YeastFab: the design and construction of standard biological parts for metabolic engineering in Saccharomyces cerevisiae. Nucleic Acids Res 43(13): e88.

 

Heikel, G., N.R. Choudhury and G. Michlewski (2016). The role of Trim25 in development, disease and RNA metabolism. Biochem Soc Trans 44(4): 1045-1050.

 

Helwak, A. and D. Tollervey (2016). Identification of miRNA-Target RNA Interactions Using CLASH. Methods Mol Biol 1358: 229-251.

 

Herbert, A.P., E. Makou, Z.A. Chen, H. Kerr, A. Richards, J. Rappsilber and P.N. Barlow (2015). Complement evasion mediated by enhancement of captured factor H: implications for protection of self-surfaces from complement. J Immunol 195(10): 4986-4998.

 

Hinshaw, S.M., V. Makrantoni, A. Kerr, A.L. Marston and S.C. Harrison (2015). Structural evidence for Scc4-dependent localization of cohesin loading. Elife 4: e06057.

 

Hoesl, M.G., S. Oehm, P. Durkin, E. Darmon, L. Peil, H.R. Aerni, J. Rappsilber, J. Rinehart, D. Leach, D. Soll and N. Budisa (2015). Chemical Evolution of a Bacterial Proteome. Angew Chem Int Ed Engl 54(34): 10030-10034.

 

Holmes, R.K., A.C. Tuck, C. Zhu, H.R. Dunn-Davies, G. Kudla, S. Clauder-Munster, S. Granneman, L.M. Steinmetz, C. Guthrie and D. Tollervey (2015). Loss of the Yeast SR Protein Npl3 Alters Gene Expression Due to Transcription Readthrough. PLoS Genet 11(12): e1005735.

 

Houston, D.R., L.H. Yen, S. Pettit and M.D. Walkinshaw (2015). Structure- and ligand-based virtual screening identifies new scaffolds for inhibitors of the oncoprotein MDM2. PLoS One 10(4): e0121424.

 

Hunziker, M., J. Barandun, E. Petfalski, D. Tan, C. Delan-Forino, K.R. Molloy, K.H. Kim, H. Dunn-Davies, Y. Shi, M. Chaker-Margot, B.T. Chait, T. Walz, D. Tollervey and S. Klinge (2016). UtpA and UtpB chaperone nascent pre-ribosomal RNA and U3 snoRNA to initiate eukaryotic ribosome assembly. Nat Commun 7: 12090.

 

Illingworth, R.S., U. Gruenewald-Schneider, D. De Sousa, S. Webb, C. Merusi, A.R. Kerr, K.D. James, C. Smith, R. Walker, R. Andrews and A.P. Bird (2015). Inter-individual variability contrasts with regional homogeneity in the human brain DNA methylome. Nucleic Acids Res 43: 732-744.

 

Imhof, A. and J. Rappsilber (2016). A Focus on Chromatin Proteomics. Proteomics 16(3): 379-380.

 

Jayachandran, U., H. Grey and A. G. Cook (2016). Nuclear factor 90 uses an ADAR2-like binding mode to recognize specific bases in dsRNA. Nucleic Acids Res 44(4): 1924-1936.

 

Kajtez, J., A. Solomatina, M. Novak, B. Polak, K. Vukusic, J. Rudiger, G. Cojoc, A. Milas, I. Sumanovac Sestak, P. Risteski, F. Tavano, A.H. Klemm, E. Roscioli, J. Welburn, D. Cimini, M. Gluncic, N. Pavin and I.M. Tolic (2016). Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores. Nat Commun 7: 10298.

 

Kanigowska, P., Y. Shen, Y. Zheng, S. Rosser and Y. Cai (2016). Smart DNA fabrication using sound waves: applying acoustic dispensing technologies to synthetic biology. J Lab Autom 21(1): 49-56.

 

Katz, D.M., A. Bird, M. Coenraads, S.J. Gray, D.U. Menon, B.D. Philpot and D.C. Tarquinio (2016). Rett Syndrome: crossing the threshold to clinical translation. Trends Neurosci 39(2): 100-113.

 

Kim, J.H., H.S. Lee, N.C. Lee, N.V. Goncharov, V. Kumeiko, H. Masumoto, W.C. Earnshaw, N. Kouprina and V. Larionov (2016). Development of a novel HAC-based "gain of signal" quantitative assay for measuring chromosome instability (CIN) in cancer cells. Oncotarget 7(12): 14841-14856.

 

Klein, D.K., S. Hoffmann, J.K. Ahlskog, K. O'Hanlon, M. Quaas, B.D. Larsen, B. Rolland, H.I. Rosner, D. Walter, A.N. Kousholt, T. Menzel, M. Lees, J.V. Johansen, J. Rappsilber, K. Engeland and C.S. Sorensen (2015). Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control. Commun 6: 5800.

 

Koehler, C., P.F. Sauter, M. Wawryszyn, G.E. Girona, K. Gupta, J.J. Landry, M.H. Fritz, K. Radic, J.E. Hoffmann, Z.A. Chen, J. Zou, P.S. Tan, B. Galik, S. Junttila, P. Stolt-Bergner, G. Pruneri, A. Gyenesei, C. Schultz, M.B. Biskup, H. Besir, V. Benes, J. Rappsilber, M. Jechlinger, J.O. Korbel, I. Berger, S. Braese and E.

Lemke, A. (2016). Genetic code expansion for multiprotein complex engineering. Nat Methods 13(12): 997-1000.

 

Kononenko, A.V., N.C. Lee, M. Liskovykh, H. Masumoto, W.C. Earnshaw, V. Larionov and N. Kouprina (2015). Generation of a conditionally self-eliminating HAC gene delivery vector through incorporation of a tTAVP64 expression cassette. Nucleic Acids Res 43(9): e57.

 

Korfali, N., L. Florens and E.C. Schirmer (2016). Isolation, proteomic analysis, and microscopy confirmation of the liver nuclear envelope proteome. Methods Mol Biol 1411: 3-44.

 

Kustatscher, G., P. Grabowski and J. Rappsilber (2016). Multiclassifier combinatorial proteomics of organelle shadows at the example of mitochondria in chromatin data. Proteomics 16(3): 393-401.

 

Kustatscher, G. and J. Rappsilber (2016). Compositional dynamics: defining the fuzzy cell. Trends Cell Biol 26(11): 800-803.

 

Le Thanh, P., P. Meinke, N. Korfali, V. Srsen, M.I. Robson, M. Wehnert, B. Schoser, C.A. Sewry and E.C. Schirmer (2016). Immunohistochemistry on a panel of Emery-Dreifuss muscular dystrophy samples reveals nuclear envelope proteins as inconsistent markers for pathology. Neuromuscul Disord. Doi.10.1016/j.nmd.2016.12.003

 

Legal, T., J. Zou, A. Sochaj, J. Rappsilber and J.P. Welburn (2016). Molecular architecture of the Dam1 complex-microtubule interaction. Open Biol 6(3).

 

Liang, S.C., B. Hartwig, P. Perera, S. Mora-Garcia, E. de Leau, H. Thornton, F. de Lima Alves, J. Rappsilber, S. Yang, G.V. James, K. Schneeberger, E.J. Finnegan, F. Turck and J. Goodrich (2015). Kicking against the PRCs - a domesticated transposase antagonises silencing mediated by polycomb group proteins and is an accessory component of polycomb repressive complex 2. PLoS Genet 11(12): e1005660.

 

Liang, S.C., B. Hartwig, P. Perera, S. Mora-Garcia, E. de Leau, H. Thornton, F. de Lima Alves, J. Rappsilber, S. Yang, G.V. James, K. Schneeberger, E.J. Finnegan, F. Turck and J. Goodrich (2016). Correction: Kicking against the PRCs--a domesticated transposase antagonises silencing mediated by polycomb group proteins and Is an Accessory Component of Polycomb Repressive Complex 2. PLoS Genet 12(2): e1005812.

 

Logsdon, G.A., E.J. Barrey, E.A. Bassett, J.E. DeNizio, L.Y. Guo, T. Panchenko, J.M. Dawicki-McKenna, P.

Heun and B.E. Black (2015). Both tails and the centromere targeting domain of CENP-A are required for centromere establishment. J Cell Biol 208(5): 521-531.

 

Lyst, M.J. and A. Bird (2015). Rett syndrome: a complex disorder with simple roots. Nat Rev Genet 16: 261-275.

 

Lyst, M.J., J. Connelly, C. Merusi and A. Bird (2016). Sequence specific DNA binding by AT-hook motifs in MeCP2. FEBS Lett. doi.10.1002/1873-3468.12328.

 

Makarov, A.A., A. Rizzotto, P. Meinke and E.C. Schirmer (2016). Purification of lamins and soluble fragments of NETs. Methods Enzymol 569: 79-100.

 

Marston, A.L. (2015). Shugoshins: tension-sensitive pericentromeric adaptors safeguarding chromosome segregation. Mol Cell Biol 35(4): 634-648.

 

Martella, A., S.M. Pollard, J. Dai and Y. Cai (2016). Mammalian Synthetic Biology: Time for Big MACs. ACS Synth Biol 5(10): 1040-1049.

 

Martins, N.M., J.H. Bergmann, N. Shono, H. Kimura, V. Larionov, H. Masumoto and W.C. Earnshaw (2016). Epigenetic engineering shows that a human centromere resists silencing mediated by H3K27me3/K9me3. Mol Biol Cell 27(1): 177-196.

 

Mayer, M.C., L. Schauenburg, G. Thompson-Steckel, V. Dunsing, D. Kaden, P. Voigt, M. Schaefer, S. Chiantia, T.E. Kennedy and G. Multhaup (2016). Amyloid precursor-like protein (APLP)1 exhibits stronger zinc-dependent neuronal adhesion than APP and APLP2. J Neurochem. 137, 266–276.

 

McCaughan, U.M., U. Jayachandran, V. Shchepachev, Z.A. Chen, J. Rappsilber, D. Tollervey and A.G. Cook (2016). Pre-40S ribosome biogenesis factor Tsr1 is an inactive structural mimic of translational GTPases. Nat Commun 7: 11789.

 

McNeil, E.M., K.R. Astell, A.M. Ritchie, S. Shave, D.R. Houston, P. Bakrania, H M. Jones, P. Khurana, C. Wallace, T. Chapman, M A. Wear, M.D. Walkinshaw, B. Saxty and D.W. Melton (2015). Inhibition of the ERCC1-XPF structure-specific endonuclease to overcome cancer chemoresistance. DNA Repair (Amst) 31: 19-28.

 

Meinke, P., A. A. Makarov, P. Lê Thành, D. Sadurska and E. C. Schirmer (2015). Nucleoskeleton dynamics and functions in health and disease. Cell Health and Cytoskeleton 7: 55-69.

 

Meinke, P. and E.C. Schirmer (2015). LINC'ing form and function at the nuclear envelope. FEBS Lett 589(19 Pt A): 2514-2521.

 

Meinke, P. and E. C. Schirmer (2016). The increasing relevance of nuclear envelope myopathies. Curr Opin Neurol 29(5): 651-661.

 

Meinke, P., P. Schneiderat, V. Srsen, N. Korfali, P. Le Thanh, G. J. Cowan, D. R. Cavanagh, M. Wehnert, E.C. Schirmer and M.C. Walter (2015). Abnormal proliferation and spontaneous differentiation of myoblasts from a symptomatic female carrier of X-linked Emery-Dreifuss muscular dystrophy. Neuromuscul Disord 25(2): 127-136.

 

Mercy, G., J. Mozziconacci, V. F. Scolari, K. Yang, G. Zhao, A. Thierry, Y. Luo, L. A. Mitchell, M. Shen, Y. Shen, R. Walker, W. Zhang, Y. Wu, Z. X. Xie, Z. Luo, Y. Cai, J. Dai, H. Yang, Y. J. Yuan, J. D. Boeke, J. S. Bader, H. Muller and R. Koszul (2017). 3D organization of synthetic and scrambled chromosomes. Science 355(6329).

 

Milligan, L., V.A. Huynh-Thu, C. Delan-Forino, A. Tuck, E. Petfalski, R. Lombrana, G. Sanguinetti, G. Kudla and D. Tollervey (2016). Strand-specific, high-resolution mapping of modified RNA polymerase II. Mol Syst Biol 12(6): 874.

 

Mitchell, L. A., J. Chuang, N. Agmon, C. Khunsriraksakul, N. A. Phillips, Y. Cai, D. M. Truong, A. Veerakumar, Y. Wang, M. Mayorga, P. Blomquist, P. Sadda, J. Trueheart and J. D. Boeke (2015). Versatile genetic assembly system (VEGAS) to assemble pathways for expression in S. cerevisiae. Nucleic Acids Res 43(13): 6620-6630.

 

Mitchell, L. A., A. Wang, G. Stracquadanio, Z. Kuang, X. Wang, K. Yang, S. Richardson, J. A. Martin, Y. Zhao, R. Walker, Y. Luo, H. Dai, K. Dong, Z. Tang, Y. Yang, Y. Cai, A. Heguy, B. Ueberheide, D. Fenyo, J. Dai, J. S. Bader and J. D. Boeke (2017). Synthesis, debugging, and effects of synthetic chromosome consolidation: synVI and beyond. Science 355(6329).

 

Molina, O., M. Carmena, I.E. Maudlin and W.C. Earnshaw (2016). PREditOR: a synthetic biology approach to removing heterochromatin from cells. Chromosome Res 24(4): 495-509.

 

Molina, O., G. Vargiu, M.A. Abad, A. Zhiteneva, A.A. Jeyaprakash, H. Masumoto, N. Kouprina, V. Larionov and W.C. Earnshaw (2016). Epigenetic engineering reveals a balance between histone modifications and transcription in kinetochore maintenance. Nat Commun 7: 13334.

 

Montano-Gutierrez, L.F., S. Ohta, G. Kustatscher, W.C. Earnshaw and J. Rappsilber (2017). Nano random forests to mine protein complexes and their relationships in quantitative proteomics data. Mol Biol Cell 28(5): 673-680.

 

Much, C., T. Auchynnikava, D. Pavlinic, A. Buness, J. Rappsilber, V. Benes, R. Allshire and D.O'Carroll (2016). Endogenous mouse dicer is an exclusively cytoplasmic protein. PLoS Genet 12(6): e1006095.

 

Mudumbi, K.C., E.C. Schirmer and W. Yang (2016). Single-point single-molecule FRAP distinguishes inner and outer nuclear membrane protein distribution. Nat Commun 7: 12562.

 

Mutavchiev, D.R., M. Leda and K.E. Sawin (2016). Remodeling of the fission yeast Cdc42 cell-polarity module via the Sty1 p38 stress-activated protein kinase pathway. Curr Biol 26(21): 2921-2928.

 

Naithani, A., P. Taylor, B. Erman and M.D. Walkinshaw (2015). A molecular dynamics study of allosteric transitions in Leishmania mexicana pyruvate kinase. Biophys J 109(6): 1149-1156.

 

Narayan, V., V. Landre, J. Ning, L. Hernychova, P. Muller, C. Verma, M.D. Walkinshaw, E.A. Blackburn and K.L. Ball (2015). Protein-protein interactions modulate the docking-dependent E3-ubiquitin ligase activity of

carboxy-terminus of Hsc70-interacting protein (CHIP). Mol Cell Proteomics 14(11): 2973-2987.

 

Nikalayevich, N. and H. Ohkura (2015). The NuRD nucleosome remodelling complex and NHK-1 kinase are required for chromosome condensation in oocytes. J. Cell Sci 128: 566-575.

 

Nowak, J.S., F. Hobor, A. Downie Ruiz Velasco, N.R. Choudhury, G. Heikel, A. Kerr, A. Ramos and G. Michlewski (2017). Lin28a uses distinct mechanisms of binding to RNA and affects miRNA levels positively and negatively. RNA 23(3): 317-332.

 

Ohkura, H. (2015). Meiosis: an overview of key differences from mitosis. Cold Spring Harb Perspect Biol 7(5).

 

Ohta, S., L.F. Montano-Gutierrez, F. de Lima Alves, H. Ogawa, I. Toramoto, N. Sato, C.G. Morrison, S. Takeda, D.F. Hudson, J. Rappsilber and W.C. Earnshaw (2016). Proteomics analysis with a nano random forest approach reveals novel functional interactions regulated by SMC complexes on mitotic chromosomes. Mol Cell Proteomics 15(8): 2802-2818.

 

Ohta, S., L. Wood, I. Toramoto, K. Yagyu, T. Fukagawa and W.C. Earnshaw (2015). CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly. Mol Biol Cell 26(7): 1225-1237.

 

Ohzeki, J., V. Larionov, W.C. Earnshaw and H. Masumoto (2015). Genetic and epigenetic regulation of centromeres: a look at HAC formation. Chromosome Res 23(1): 87-103.

 

Ohzeki, J., N. Shono, K. Otake, N.M. Martins, K. Kugou, H. Kimura, T. Nagase, V. Larionov, W.C. Earnshaw and H. Masumoto (2016). KAT7/HBO1/MYST2 regulates CENP-A chromatin assembly by antagonizing Suv39h1-mediated centromere inactivation. Dev Cell 37(5): 413-427.

 

Papini, D., L. Langemeyer, M.A. Abad, A. Kerr, I. Samejima, P.A. Eyers, A.A. Jeyaprakash, J.M. Higgins, F.A. Barr and W.C. Earnshaw (2015). TD-60 links RalA GTPase function to the CPC in mitosis. Nat Commun 6: 7678.

 

Platani, M., L. Trinkle-Mulcahy, M. Porter, A.A. Jeyaprakash and W.C. Earnshaw (2015). Mio depletion links mTOR regulation to Aurora A and Plk1 activation at mitotic centrosomes. J Cell Biol 210(1): 45-62.

 

Puchta, O., B. Cseke, H. Czaja, D. Tollervey, G. Sanguinetti and G. Kudla (2016). Network of epistatic interactions within a yeast snoRNA. Science 352(6287): 840-844.

 

Quante, T. and A. Bird (2016). Do short, frequent DNA sequence motifs mould the epigenome? Nat Rev Mol Cell Biol 17(4): 257-262.

 

Qin, Y., C. Tan, J. Lin, Q. Qin, J. He, Q. Wu, Y. Cai, Z. Chen and J. Dai (2016). EcoExpress-highly efficient construction and expression of multicomponent protein complexes in Escherichia coli. ACS Synth Biol 5(11): 1239-1246.

 

Quinn, J.Y., R.S. Cox, 3rd, A. Adler, J. Beal, S. Bhatia, Y. Cai, J. Chen, K. Clancy, M. Galdzicki, N.J. Hillson, N. Le Novere, A.J. Maheshwari, J.A. McLaughlin, C.J. Myers, U.P, M. Pocock, C. Rodriguez, L. Soldatova, G.B. Stan, N. Swainston, A. Wipat and H.M. Sauro (2015). SBOL Visual: a graphical language for genetic designs. PLoS Biol 13(12): e1002310.

 

Radford, S.J., T.L. Hoang, A.A. Gluszek, H. Ohkura and K.S. McKim (2015). Lateral and end-on kinetochore attachments are coordinated to achieve bi-orientation in Drosophila oocytes. PLoS Genet 11(10): e1005605.

 

Richardson, S.M., L.A. Mitchell, G. Stracquadanio, K. Yang, J.S. Dymond, J.E. DiCarlo, D. Lee, C.L. Huang, S. Chandrasegaran, Y. Cai, J.D. Boeke and J.S. Bader (2017). Design of a synthetic yeast genome. Science 355(6329): 1040-1044.

 

Robson, M.I., J.I. de Las Heras, R. Czapiewski, P. Le Thanh, D.G. Booth, D.A. Kelly, S. Webb, A.R. Kerr and E. C. Schirmer (2016). Tissue-specific gene repositioning by muscle nuclear membrane proteins enhances repression of critical developmental genes during myogenesis. Mol Cell 62(6): 834-847.

 

Robson, M.I., J.I. de las Heras, A.R.W. Kerr and E.C. Schirmer (2017). Lymphocyte genes and an enhancer sequestered at the nuclear periphery undergo constrained release and associate upon T-cell activation. bioRxiv http://dx.doi.org/10.1101/062224.

 

Robson, M.I. and E.C. Schirmer (2016). The application of DamID to identify peripheral gene sequences in differentiated and primary cells. Methods Mol Biol 1411: 359-386.

 

Ross, P.D., J. Guy, J. Selfridge, B. Kamal, N. Bahey, E. Tanner, T.H. Gillingwater, R.A. Jones, C.M. Loughrey, C.S. McCarroll, M.E. Bailey, A. Bird and S. Cobb (2016). Exclusive expression of MeCP2 in the nervous system distinguishes between brain and peripheral Rett syndrome-like phenotypes. Hum Mol Genet. 25: 4389-4404.

 

Saiz-Ros, N., R. Czapiewski, A. Stevenson, I. Epifano, S.K. Swanson, M. McElwee, S. Vijayakrishnan, C.A. Richardson, C.R. Dixon, L. Pytowski, M.W. Goldberg, L. Florens, S.V. Graham and E.C. Schirmer (2017). Host vesicle fusion proteins VAPB, Rab11b and Rab18 contribute to HSV-1 infectivity by facilitating egress through the nuclear membrane. bioRxiv http://dx.doi.org/10.1101/088633.

 

Saka, Y., C.V. Giuraniuc and H. Ohkura (2015). Accurate chromosome segregation by probabilistic self-organisation. BMC Biol 13: 65.

 

Sali, A., H.M. Berman, T. Schwede, J. Trewhella, G. Kleywegt, S.K. Burley, J. Markley, H. Nakamura, P. Adams, A.M. Bonvin, W. Chiu, M.D. Peraro, F. Di Maio, T.E. Ferrin, K. Grunewald, A. Gutmanas, R. Henderson, G. Hummer, K. Iwasaki, G. Johnson, C.L. Lawson, J. Meiler, M.A. Marti-Renom, G.T. Montelione, M. Nilges, R. Nussinov, A. Patwardhan, J. Rappsilber, R.J. Read, H. Saibil, G.F. Schroder, C.D. Schwieters, C.A. Seidel, D. Svergun, M. Topf, E.L. Ulrich, S. Velankar and J.D. Westbrook (2015). Outcome of the First wwPDB Hybrid/Integrative Methods Task Force Workshop. Structure 23(7): 1156-1167.

 

Samejima, I., C. Spanos, L. Alves Fde, T. Hori, M. Perpelescu, J. Zou, J. Rappsilber, T. Fukagawa and W.C. Earnshaw (2015). Whole-proteome genetic analysis of dependencies in assembly of a vertebrate kinetochore. J Cell Biol 211(6): 1141-1156.

 

Samejima, K., M. Platani, M. Wolny, H. Ogawa, G. Vargiu, P.J. Knight, M. Peckham and W.C. Earnshaw (2015). The Inner Centromere Protein (INCENP) coil is a Single Alpha-Helix (SAH) domain that binds directly to microtubules and is important for Chromosome Passenger Complex (CPC) localization and function in mitosis. J Biol Chem 290(35): 21460-21472.

 

Sardana, R., X. Liu, S. Granneman, J. Zhu, M. Gill, O. Papoulas, E.M. Marcotte, D. Tollervey, C.C. Correll and A. W. Johnson (2015). The DEAH-box helicase Dhr1 dissociates U3 from the pre-rRNA to promote formation of the central pseudoknot. PLoS Biol 13(2): e1002083.

 

Schneider, M., A. Belsom, J. Rappsilber and O. Brock (2016). Blind testing of cross-linking/mass spectrometry hybrid methods in CASP11. Proteins 84 Suppl 1: 152-163.

 

Shah, R.R. and A.P. Bird (2017). MeCP2 mutations: progress towards understanding and treating Rett Syndrome. Genome Med 9(1): 17.

 

Shave, S., E.A. Blackburn, J. Adie, D.R. Houston, M. Auer, S.P. Webster, P. Taylor and M.D. Walkinshaw (2015). UFSRAT: Ultra-fast shape recognition with atom types - the discovery of novel bioactive small molecular scaffolds for FKBP12 and 11betaHSD1. PLoS One 10(2): e0116570.

 

Shchepachev, V. and D. Tollervey (2016). Motoring toward pre-60S-ribosome export. Nat Struct Mol Biol 23(1): 3-4.

 

Shen, Y., G. Stracquadanio, Y. Wang, K. Yang, L. A. Mitchell, Y. Xue, Y. Cai, T. Chen, J. S. Dymond, K. Kang, J. Gong, X. Zeng, Y. Zhang, Y. Li, Q. Feng, X. Xu, J. Wang, J. Wang, H. Yang, J. D. Boeke and J. S. Bader (2016). SCRaMbLE generates designed combinatorial stochastic diversity in synthetic chromosomes. Genome Res 26(1): 36-49.

 

 

Sheppard, C., F. Blombach, A. Belsom, S. Schulz, T. Daviter, K. Smollett, E. Mahieu, S. Erdmann, P. Tinnefeld, R. Garrett, D. Grohmann, J. Rappsilber and F. Werner (2016). Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP. Nat Commun 7: 13595.

 

Shono, N., J. Ohzeki, K. Otake, N.M. Martins, T. Nagase, H. Kimura, V. Larionov, W.C. Earnshaw and H. Masumoto (2015). CENP-C and CENP-I are key connecting factors for kinetochore and CENP-A assembly. J Cell Sci 128(24): 4572-4587.

 

Soukarieh, F., M.W. Nowicki, A. Bastide, T. Poyry, C. Jones, K. Dudek, G. Patwardhan, F. Meullenet, N.J. Oldham, M.D. Walkinshaw, A.E. Willis and P.M. Fischer (2016). Design of nucleotide-mimetic and non-nucleotide inhibitors of the translation initiation factor eIF4E: Synthesis, structural and functional characterisation. Eur J Med Chem 124: 200-217.

 

Subramanian, L., B. Medina-Pritchard, R. Barton, F. Spiller, R. Kulasegaran-Shylini, G. Radaviciute, R.C.

Allshire and A. Arockia Jeyaprakash (2016). Centromere localization and function of Mis18 requires Yippee-like domain-mediated oligomerization. EMBO Rep 17(4): 496-507.

 

Svensson, J.P., M. Shukla, V. Menendez-Benito, U. Norman-Axelsson, P. Audergon, I. Sinha, J.C. Tanny, R. C. Allshire and K. Ekwall (2015). A nucleosome turnover map reveals that the stability of histone H4 Lys20 methylation depends on histone recycling in transcribed chromatin. Genome Res 25(6): 872-883.

 

Talapatra, S. K., B. Harker and J. P. Welburn (2015). The C-terminal region of the motor protein MCAK controls its structure and activity through a conformational switch. Elife 4.

 

Tollervey, D. (2015). RNA surveillance and the exosome. RNA 21(4): 492-493.

 

Tomko, R. J., Jr., D. W. Taylor, Z. A. Chen, H. W. Wang, J. Rappsilber and M. Hochstrasser (2015). A single alpha helix drives extensive remodeling of the proteasome lid and completion of regulatory particle assembly. Cell 163(2): 432-444.

 

Trowitzsch, S., C. Viola, E. Scheer, S. Conic, V. Chavant, M. Fournier, G. Papai, I. O. Ebong, C. Schaffitzel, J. Zou, M. Haffke, J. Rappsilber, C.V. Robinson, P. Schultz, L. Tora and I. Berger (2015). Cytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID assembly from preformed submodules. Nat Commun 6: 6011.

 

Trubitsyna, M., G. Michlewski, D. J. Finnegan, A. Elfick, S. J. Rosser, J. M. Richardson and C. E. French (2017). Use of mariner transposases for one-step delivery and integration of DNA in prokaryotes and eukaryotes by transfection. Nucleic Acids Res. (in press)

 

Turowski, T.W., E. Lesniewska, C. Delan-Forino, C. Sayou, M. Boguta and D. Tollervey (2016). Global analysis of transcriptionally engaged yeast RNA polymerase III reveals extended tRNA transcripts. Genome Res 26(7): 933-944.

 

Turowski, T.W. and D. Tollervey (2015). Cotranscriptional events in eukaryotic ribosome synthesis. Wiley Interdiscip Rev RNA 6(1): 129-139.

 

Turowski, T.W. and D. Tollervey (2016). Transcription by RNA polymerase III: insights into mechanism and regulation. Biochem Soc Trans 44(5): 1367-1375.

 

Vincenten, N., L.M. Kuhl, I. Lam, A. Oke, A.R. Kerr, A. Hochwagen, J. Fung, S. Keeney, G. Vader and A.L. Marston (2015). The kinetochore prevents centromere-proximal crossover recombination during meiosis. Elife 4.

 

Walker, R.S. and Y. Cai (2016). The Fifth Annual Sc2.0 and Synthetic Genomes Conference: Synthetic Genomes in High Gear. ACS Synth Biol 5(9): 920-922.

 

Wallace, E.W. and J. Beggs (2017). Extremely fast and incredibly close: co-transcriptional splicing in budding yeast. RNA 23, doi: 10.1261/rna.060830

 

Walter, D., S. Hoffmann, E.S. Komseli, J. Rappsilber, V. Gorgoulis and C. S. Sorensen (2016). SCF(Cyclin F)-dependent degradation of CDC6 suppresses DNA re-replication. Nat Commun 7: 10530.

 

Wandrey, F., C. Montellese, K. Koos, L. Badertscher, L. Bammert, A.G. Cook, I. Zemp, P. Horvath and U. Kutay (2015). The NF45/NF90 heterodimer contributes to the biogenesis of 60S ribosomal subunits and influences nucleolar morphology. Mol Cell Biol 35(20): 3491-3503.

 

Waters, S.A., S.P. McAteer, G. Kudla, I. Pang, N.P. Deshpande, T.G. Amos, K.W. Leong, M.R. Wilkins, R. Strugnell, D.L. Gally, D. Tollervey and J.J. Tree (2017). Small RNA interactome of pathogenic E. coli revealed through crosslinking of RNase E. EMBO J 36(3): 374-387.

 

Wear, M.A., M.W. Nowicki, E.A. Blackburn, I.W. McNae and M.W. Walkinshaw (2017). Thermo‐kinetic analysis space expansion for cyclophilin‐ligand interactions–identification of a new non‐peptide inhibitor using Biacore™ T200. FEBS Open Bio (in press).

 

Welburn, J. (2015). Cell Scientists to watch - Julie Welburn interview. J Cell Sci 128: 4465-4466.

 

Wood, L., D.G. Booth, G. Vargiu, S. Ohta, F. deLima Alves, K. Samejima, T. Fukagawa, J. Rappsilber and W.C.

Earnshaw (2016). Auxin/AID versus conventional knockouts: distinguishing the roles of CENP-T/W in mitotic kinetochore assembly and stability. Open Biol 6(1).

 

Worman, H.J. and E.C. Schirmer (2015). Nuclear membrane diversity: underlying tissue-specific pathologies in disease? Curr Opin Cell Biol 34: 101-112.

 

Wu, X., I.H. Bekker-Jensen, J. Christensen, K.D. Rasmussen, S. Sidoli, Y. Qi, Y. Kong, X. Wang, Y. Cui, Z. Xiao, G. Xu, K. Williams, J. Rappsilber, C.K. Sonderby, O. Winther, O.N. Jensen and K. Helin (2015). Tumor suppressor ASXL1 is essential for the activation of INK4B expression in response to oncogene activity and anti-proliferative signals. Cell Res 25(11): 1205-1218.

 

Wu, Y., B.Z. Li, M. Zhao, L.A. Mitchell, Z.X. Xie, Q.H. Lin, X. Wang, W.H. Xiao, Y. Wang, X. Zhou, H. Liu, X. Li, M.Z. Ding, D. Liu, L. Zhang, B.L. Liu, X.L. Wu, F.F. Li, X.T. Dong, B. Jia, W.Z. Zhang, G.Z. Jiang, Y. Liu, X. Bai, T.Q. Song, Y. Chen, S.J. Zhou, R.Y. Zhu, F. Gao, Z. Kuang, X. Wang, M. Shen, K. Yang, G. Stracquadanio, S.M. Richardson, Y. Lin, L. Wang, R. Walker, Y. Luo, P.S. Ma, H. Yang, Y. Cai, J. Dai, J.S. Bader, J.D. Boeke and Y.J. Yuan (2017). Bug mapping and fitness testing of chemically synthesized chromosome X. Science 355(6329).

 

Xie, Z.X., B.Z. Li, L.A. Mitchell, Y. Wu, X. Qi, Z. Jin, B. Jia, X. Wang, B.X. Zeng, H.M. Liu et al (2017). “Perfect" designer chromosome V and behavior of a ring derivative. Science 355(6329).

 

Ye, A.A., J. Deretic, C.M. Hoel, A.W. Hinman, D. Cimini, J.P. Welburn and T.J. Maresca (2015). Aurora A Kinase contributes to a pole-based error correction pathway. Curr Biol 25(14): 1842-1851.

 

Yuan, Z., A. Riera, L. Bai, J. Sun, S. Nandi, C. Spanos, Z.A. Chen, M. Barbon, J. Rappsilber, B. Stillman, C. Speck and H. Li (2017). Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1. Nat Struct Mol Biol 24(3): 316-324.

 

Zhang, T., A. Termanis, B. Ozkan, X.X. Bao, J. Culley, F. de Lima Alves, J. Rappsilber, B. Ramsahoye and I. Stancheva (2016). G9a/GLP Complex Maintains Imprinted DNA Methylation in Embryonic Stem Cells. Cell Rep 15(1): 77-85.

 

Zhaunova, L., H. Ohkura and M. Breuer (2016). Kdm5/Lid regulates chromosome architecture in meiotic prophase I independently of its histone demethylase activity. PLoS Genet 12(8): e1006241.

 

Zhdanov R., E.C. Schirmer, A.V. Venkatasubramani, A.R.W. Kerr, E. Mandrou, G. Rodriguez-Blanco, A. Kagansky (2015). A subset of cellular lipids may provide a new dimension of epigenetic regulation through control over the structure and functions of chromatin. Science Open https://www.scienceopen.com/document_file/10c602eb-4360-45f9-9d38 2a10201bfd20/ScienceOpen/Lipids_in_Epigenetics_Review.pdf.

 

Zich, J., K. May, K. Paraskevopoulos, O. Sen, H.M. Syred, S. van der Sar, H. Patel, J.J. Moresco, A. Sarkeshik, J.R. Yates, 3rd, J. Rappsilber and K. Hardwick (2016). Mps1Mph1 kinase phosphorylates Mad3 to inhibit Cdc20Slp1-APC/C and maintain spindle checkpoint arrests. PLoS Genet 12(2): e1005834.

 

Zich, J., K. May, K. Paraskevopoulos, O. Sen, H. M. Syred, S. van der Sar, H. Patel, J.J. Moresco, A. Sarkeshik, J.R. Yates, 3rd, J. Rappsilber and K.G. Hardwick (2016). Correction: Mps1Mph1 Kinase Phosphorylates Mad3 to Inhibit Cdc20Slp1-APC/C and Maintain Spindle Checkpoint Arrests. PLoS Genet 12(4): e1006009.

 

 

 

 

Centre Publications

2015 – 2017

 

Abad, M.A., J. Zou, B. Medina-Pritchard, E.A. Nigg, J. Rappsilber, A. Santamaria and A.A. Jeyaprakash (2016). Ska3 ensures timely mitotic progression by interacting directly with microtubules and Ska1 microtubule binding domain. Sci Rep 6: 34042.

 

Agirre, X., G. Castellano, M. Pascual, S. Heath, M. Kulis, V. Segura, A. Bergmann, A. Esteve, A. Merkel, E. Raineri, L. Agueda, J. Blanc, D. Richardson, L. Clarke, A. Datta, N. Russinol, A.C. Queiros, R. Beekman, J.R. Rodriguez-Madoz, E.S. Jose-Eneriz, F. Fang, N.C. Gutierrez, J.M. Garcia-Verdugo, M.I. Robson, E.C. Schirmer, et al (2015). Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers. Genome Res 25: 478-487.

 

Agmon, N., Z. Tang, K. Yang, B. Sutter, S. Ikushima, Y. Cai, K. Caravelli, J.A. Martin, X. Sun, W.J. Choi, A. Zhang, G. Stracquadanio, H. Hao, B.P. Tu, D. Fenyo, J.S. Bader and J.D. Boeke (2017). Low escape-rate genome safeguards with minimal molecular perturbation of Saccharomyces cerevisiae. Proc Natl Acad Sci USA 114(8): E1470-E1479.

 

Agmon, N., L.A. Mitchell, Y. Cai, S. Ikushima, J. Chuang, A. Zheng, W.J. Choi, J.A. Martin, K. Caravelli, G. Stracquadanio and J.D. Boeke (2015). Yeast Golden Gate (yGG) for the Efficient Assembly of S. cerevisiae Transcription Units. ACS Synth Biol 4(7): 853-859.

 

Allshire, R.C. and K. Ekwall (2015). Epigenetic Regulation of Chromatin States in Schizosaccharomyces pombe. Cold Spring Harb Perspect Biol 7(7): a018770.

 

Ard, R. and R.C. Allshire (2016). Transcription-coupled changes to chromatin underpin gene silencing by transcriptional interference. Nucleic Acids Res 44(22): 10619-10630.

 

Audergon, P.N., S. Catania, A. Kagansky, P. Tong, M. Shukla, A.L. Pidoux and R.C. Allshire (2015). Epigenetics. Restricted epigenetic inheritance of H3K9 methylation. Science 348(6230): 132-135.

 

Barrass, J.D., J.E. Reid, Y. Huang, R.D. Hector, G. Sanguinetti, J.D. Beggs and S. Granneman (2015). Transcriptome-wide RNA processing kinetics revealed using extremely short 4tU labeling. Genome Biol 16: 282.

 

Barysz, H., J.H. Kim, Z.A. Chen, D.F. Hudson, J. Rappsilber, D.L. Gerloff and W.C. Earnshaw (2015). Three-dimensional topology of the SMC2/SMC4 subcomplex from chicken condensin I revealed by cross-linking and molecular modelling. Open Biol 5(2): 150005.

 

Batrakou, D.G., J.I. de Las Heras, R. Czapiewski, R. Mouras and E.C. Schirmer (2015). TMEM120A and B: nuclear envelope transmembrane proteins important for adipocyte differentiation. PLoS One 10(5): e0127712.

 

Beaven, R., N.S. Dzhindzhev, Y. Qu, I. Hahn, F. Dajas-Bailador, H. Ohkura and A. Prokop (2015). Drosophila CLIP-190 and mammalian CLIP-170 display reduced microtubule plus end association in the nervous system. Mol Biol Cell 26: 1491-1508.

 

Belsom, A., M. Schneider, O. Brock and J. Rappsilber (2016). Blind evaluation of hybrid protein structure analysis methods based on cross-linking. Trends Biochem Sci 41(7): 564-567.

 

Belsom, A., M. Schneider, L. Fischer, O. Brock and J. Rappsilber (2016). Serum albumin domain structures in human blood serum by mass spectrometry and computational biology. Mol Cell Proteomics 15(3): 1105-1116.

 

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