Ska3 Ensures Timely Mitotic Progression by Interacting Directly With Microtubules and Ska1 Microtubule Binding Domain.

Abad, M.A., Zou, J, Medina-Pritchard, B, Nigg, E.A., Rappsilber, J, Santamaria, A. Jeyaprakash, A.A.

Scientific Reports (2016) 6, Article number: 34042

 

 

 

 

In this work, we show that the Ska3 C-terminal domain modulates the microtubule binding activity of the Ska complex by directly interacting with microtubules and Ska1 microtubule binding domain.  This modulatory role of Ska3 is required for timely onset of anaphase.

Journal Link:

http://www.nature.com/articles/srep34042

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