Pervasive coexpression of spatially proximal genes is buffered at the protein level

Kustatscher, G., Grabowski, P., Rappsilber, J.

Mol Syst Biol (2017) 13: 937

 

Housekeeping genes are clustered in the human genome, which minimizes stochastic silencing but leads to partial coexpression of thousands of functionally unrelated genes. This non‐functional mRNA coexpression is buffered at the protein level.

Journal Link:

http://msb.embopress.org/content/13/8/937

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