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Molecular basis for Cdk1-regulated timing of Mis18 complex assembly and CENP-A deposition

Spiller, F., Medina-Pritchard, B., Abad, M.A., Wear, M.A., Molina, O., Earnshaw, W.C., Jeyaprakash, A.A.

EMBO reports (2017) 18, 894-905

The cell cycle‐dependent assembly of the Mis18 complex is essential for HJURP‐mediated CENP‐A deposition at centromeres. This study presents the molecular basis for how the Mis18 complex is assembled and how Cdk1 times the assembly.

doi: 10.15252/embr.201643564

Journal Link:

http://embor.embopress.org/content/18/6/894

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