High-resolution mapping of centromeric protein association using APEX-chromatin fibers

Kyriacou, E., Heun, P.

Epigenetics & Chromatin (2018) 11, 68

The centromere is a specialised chromosomal locus that forms the kinetochore and ensures faithful chromosome segregation. In this paper, we present a novel microscopy-based approach called “APEX-chromatin fibers” for localising protein binding over the repetitive centromeric sequences at kilobase resolution.

 

Journal Link:

https://epigeneticsandchromatin.biomedcentral.com/articles/10.1186/s13072-018-0237-6

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